K
Keith A. Cengel
Researcher at University of Pennsylvania
Publications - 210
Citations - 12705
Keith A. Cengel is an academic researcher from University of Pennsylvania. The author has contributed to research in topics: Lung cancer & Medicine. The author has an hindex of 34, co-authored 178 publications receiving 10610 citations. Previous affiliations of Keith A. Cengel include University of Illinois at Urbana–Champaign & Hospital of the University of Pennsylvania.
Papers
More filters
Journal ArticleDOI
Radical pleurectomy and intraoperative photodynamic therapy for malignant pleural mesothelioma.
Joseph S. Friedberg,Melissa Culligan,Rosemarie Mick,James P. Stevenson,Stephen M. Hahn,Daniel H. Sterman,Salman Punekar,Eli Glatstein,Keith A. Cengel +8 more
TL;DR: It was possible to achieve a macroscopic complete resection using lung-sparing surgery in 97% of these patients with stage III/IV disease and the survival the authors observed was unusually long for the patients with the epithelial subtype but, interestingly, the PFS was not.
Journal ArticleDOI
Class I PI3 Kinase Inhibition by the Pyridinylfuranopyrimidine Inhibitor PI-103 Enhances Tumor Radiosensitivity
Remko Prevo,Eric Deutsch,Oliver Sampson,Julie Diplexcito,Keith A. Cengel,Jane Harper,Peter O'Neill,W. Gillies McKenna,Sonal Patel,Eric J. Bernhard +9 more
TL;DR: Results show that inhibiting PI3K activity reduces phosphorylation of AKT at serine 473, and indicate that pharmacologic inhibitors with enhanced specificity for class IPI3K may be of benefit when combined with radiotherapy.
Journal ArticleDOI
Limitations in predicting the space radiation health risk for exploration astronauts.
Jeffery C. Chancellor,Rebecca S. Blue,Keith A. Cengel,Serena M. Auñón-Chancellor,Kathleen H. Rubins,Helmut G. Katzgraber,Helmut G. Katzgraber,Ann R. Kennedy +7 more
TL;DR: In this paper, the authors highlight the numerous factors that limit understanding of the risk of space radiation for human crews and identify ways in which these limitations could be addressed for improved understanding and appropriate risk posture regarding future human spaceflight.
Journal ArticleDOI
Motexafin lutetium-photodynamic therapy of prostate cancer: short- and long-term effects on prostate-specific antigen.
Hiral R. Patel,Rosemarie Mick,Jarod C. Finlay,Timothy C. Zhu,Elizabeth Rickter,Keith A. Cengel,S. Bruce Malkowicz,Stephen M. Hahn,Theresa M. Busch +8 more
TL;DR: Results show PDT to induce large, transient increases in serum PSA levels, and patients who experienced high PDT dose showed greater short-term increase in PSA and a significantly more durable PSA response (biochemical delay).
Journal ArticleDOI
Dietary flaxseed prevents radiation-induced oxidative lung damage, inflammation and fibrosis in a mouse model of thoracic radiation injury
James C. Lee,Ryan Krochak,Aaron Blouin,Stathis Kanterakis,Shampa Chatterjee,Evguenia Arguiri,Anil Vachani,Charalambos C. Solomides,Keith A. Cengel,Melpo Christofidou-Solomidou +9 more
TL;DR: It is suggested that dietary flaxseed may be clinically useful as an agent to increase the therapeutic index of thoracic XRT by increasing the radiation tolerance of lung tissues.