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Keith A. Cengel
Researcher at University of Pennsylvania
Publications - 210
Citations - 12705
Keith A. Cengel is an academic researcher from University of Pennsylvania. The author has contributed to research in topics: Lung cancer & Medicine. The author has an hindex of 34, co-authored 178 publications receiving 10610 citations. Previous affiliations of Keith A. Cengel include University of Illinois at Urbana–Champaign & Hospital of the University of Pennsylvania.
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Journal Article
Effects of anti-EGFR antibody cetuximab on androgen-independent prostate cancer cells.
TL;DR: Persistent activation of EGFR downstream signaling likely contributes to cell resistance to cetuximab, and this study examined the effects of anti-EGFR antibody cetUXimab on two human androgen-independent prostate carcinoma cell lines.
Journal ArticleDOI
Prospective Trial of Circulating Tumor Cells as a Biomarker for Early Detection of Recurrence in Patients with Locally Advanced Non–Small Cell Lung Cancer Treated with Chemoradiation Therapy
Chidambaram Chinniah,L. Aguarin,Phillip Cheng,C. DeCesaris,Alicia Cutillo,Abigail T. Berman,Melissa A. Frick,William P. Levin,Keith A. Cengel,Stephen M. Hahn,Jay F. Dorsey,Gary D. Kao,Charles B. Simone +12 more
Journal ArticleDOI
Evaluation of Light Fluence Distribution Using an IR Navigation System for HPPH‐mediated Pleural Photodynamic Therapy (pPDT)
Timothy C. Zhu,Yi Hong Ong,Michele M. Kim,Xing Liang,Jarod C. Finlay,Andreea Dimofte,Charles B. Simone,Joseph S. Friedberg,Theresa M. Busch,Eli Glatstein,Keith A. Cengel +10 more
TL;DR: It is concluded that it is feasible to use an IR camera‐based system to track the motion of the light source during PDT and demonstrate its use to quantify the uniformity of light distribution, which deviated by a standard deviation of 18% from the prescribed light dose.
Journal ArticleDOI
Phosphatidylinositol 3'-kinase associates with an insulin receptor substrate-1 serine kinase distinct from its intrinsic serine kinase.
TL;DR: It is found that PI 3-kinase immune complexes contain 5-fold more wortmannin-insensitive serine kinase activity than SH2-containing protein tyrosine phosphatase-2 (SHP2) and IRS-1 immune complexes.
Proceedings ArticleDOI
In-vivo light dosimetry for HPPH-mediated pleural PDT
Andreea Dimofte,Timothy C. Zhu,Jarod C. Finlay,Melissa Cullighan,Christine E Edmonds,Joseph S. Friedberg,Keith A. Cengel,Stephen M. Hahn +7 more
TL;DR: The light fluence (rate) delivered to patients undergoing pleural PDT as a function of treatment time, treatment volume and surface area is examined to establish a correlation between the treatment time and the treatment volume.