K
Keith A. Cengel
Researcher at University of Pennsylvania
Publications - 210
Citations - 12705
Keith A. Cengel is an academic researcher from University of Pennsylvania. The author has contributed to research in topics: Lung cancer & Medicine. The author has an hindex of 34, co-authored 178 publications receiving 10610 citations. Previous affiliations of Keith A. Cengel include University of Illinois at Urbana–Champaign & Hospital of the University of Pennsylvania.
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Journal ArticleDOI
PDT dose dosimetry for Photofrin-mediated pleural photodynamic therapy (pPDT)
Yi Hong Ong,Michele M. Kim,Jarod C. Finlay,Andreea Dimofte,Sunil Singhal,Eli Glatstein,Keith A. Cengel,Timothy C. Zhu +7 more
TL;DR: A four-channel PDT dose Dosimetry system to simultaneously acquire light dosimetry and photosensitizer fluorescence data and an empirical optical property correction function using Monte Carlo simulations of fluorescence for a range of physiologically relevant tissue optical properties is determined.
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Extrapleural pneumonectomy, photodynamic therapy and intensity modulated radiation therapy for the treatment of malignant pleural mesothelioma.
TL;DR: The experience with a multimodality approach for the treatment of mesothelioma, incorporating extrapleural pneumonectomy, intraoperative photodynamic therapy and postoperative hemithoracic IMRT, appears safe and effective.
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Using electron beam radiation to simulate the dose distribution for whole body solar particle event proton exposure
TL;DR: The novel concept of using megavoltage electron beam radiation to more accurately reproduce both the total dose and the dose distribution of SPE protons and make meaningful RBE comparisons between protonsand conventional radiation is described.
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Immunotherapy and radiation therapy for malignant pleural mesothelioma
TL;DR: The rationale for combining immunotherapy with radiation therapy, and early literature on this treatment combination are described, which may allow for complimentary immunologic effects that can enhance antitumor response.
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Proteasome inhibitor bortezomib is a novel therapeutic agent for focal radiation-induced osteoporosis
Abhishek Chandra,Abhishek Chandra,Luqiang Wang,Tiffany Young,Leilei Zhong,Wei Ju Tseng,Michael A. Levine,Michael A. Levine,Keith A. Cengel,X. Sherry Liu,Yejia Zhang,Yejia Zhang,Robert J. Pignolo,Ling Qin +13 more
TL;DR: A novel role of proteasome inhibitors is demonstrated in treating radiation‐induced osteoporosis by reversing the loss of trabecular bone structure and strength in mice at 4 wk after focal radiation and suppressing the number and activity of osteoclasts, regardless of irradiation.