K
Keith A. Cengel
Researcher at University of Pennsylvania
Publications - 210
Citations - 12705
Keith A. Cengel is an academic researcher from University of Pennsylvania. The author has contributed to research in topics: Lung cancer & Medicine. The author has an hindex of 34, co-authored 178 publications receiving 10610 citations. Previous affiliations of Keith A. Cengel include University of Illinois at Urbana–Champaign & Hospital of the University of Pennsylvania.
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Journal ArticleDOI
Comparison of FLASH Proton Entrance and the Spread-Out Bragg Peak Dose Regions in the Sparing of Mouse Intestinal Crypts and in a Pancreatic Tumor Model
Michele M. Kim,Ioannis I. Verginadis,Denisa Goia,Allison Haertter,Khayrullo Shoniyozov,Wei Zou,Amit Maity,Theresa M. Busch,James M. Metz,Keith A. Cengel,Lei Dong,Costas Koumenis,Eric S. Diffenderfer +12 more
TL;DR: In this article, the effects of FLASH proton radiotherapy (F-PRT) using an SOBP and the entrance region were compared to standard dose-ratio Proton Radiotherapy (S-PRTs) in mouse intestine.
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Hemithoracic radiotherapy for mesothelioma: lack of benefit or lack of statistical power?
TL;DR: In response to Katz and Husain’s question about additional endpoints for future trials comparing surgery with SABR, work by us and others suggests that inclusion of the patient-reported endpoints of global health-related quality of life and indirect costs and immune response activation after both S ABR and surgery is very informative.
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Comparative analysis of colorimetric staining in skin using open-source software.
TL;DR: A novel, straightforward method to assess colorimetric staining by combining features from two open‐source software programs is developed and demonstrated by analysing changes in skin melanin deposition during the radiation‐induced tanning response of Yucatan mini‐pigs.
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Individually ventilated cages cause chronic low-grade hypoxia impacting mice hematologically and behaviorally.
Jason M. York,Allison W. McDaniel,Neil A. Blevins,Riley R. Guillet,Sarah O Allison,Keith A. Cengel,Gregory G. Freund +6 more
TL;DR: Data indicate that ventilated caging systems can have a 0.5% reduction from ambient oxygen concentration that is coupled to mouse red blood cell indices indicative of chronic exposure to a hypoxia, and IVC housing can impact behavioral testing for depressive-like behavior.
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Molecular targets for altering radiosensitivity : Lessons from Ras as a pre-clinical and clinical model
TL;DR: In conclusion, inhibiting Ras activation represents a promising molecular approach for radiosensitization in cancer therapy.