K
Kenji Kanekiyo
Researcher at Aino University
Publications - 10
Citations - 193
Kenji Kanekiyo is an academic researcher from Aino University. The author has contributed to research in topics: Transplantation & Spinal cord. The author has an hindex of 8, co-authored 10 publications receiving 167 citations.
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Journal ArticleDOI
Loss of branched O-mannosyl glycans in astrocytes accelerates remyelination.
Kenji Kanekiyo,Kei-ichiro Inamori,Shinobu Kitazume,Keiko Sato,Jun Maeda,Makoto Higuchi,Yasuhiko Kizuka,Hiroaki Korekane,Ichiro Matsuo,Koichi Honke,Naoyuki Taniguchi +10 more
TL;DR: Together, branched O-mannosyl glycans in the corpus callosum in the brain are a necessary component of remyelination inhibition in the cuprizone-induced demyelinations model, suggesting that modulation of O- Mannosyl glycan glycans is a likely candidate for therapeutic strategies.
Journal ArticleDOI
Effects of Intrathecal Injection of the Conditioned Medium from Bone Marrow Stromal Cells on Spinal Cord Injury in Rats
Kenji Kanekiyo,Tamami Wakabayashi,Norihiko Nakano,Yoshihiro Yamada,Masahiro Tamachi,Yoshihisa Suzuki,Masatoshi Fukushima,Fukuki Saito,Seiya Abe,Chihiro Tsukagoshi,Chimi Miyamoto,Chizuka Ide +11 more
TL;DR: Activation of the intrinsic ability of the spinal cord to regenerate by the injection of neurotrophic factors such as BMSC-CM is considered to be a safe and preferable method for the clinical treatment of SCI.
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Identification of Ectonucleotide Pyrophosphatase/Phosphodiesterase 3 (ENPP3) as a Regulator of N-Acetylglucosaminyltransferase GnT-IX (GnT-Vb)
Hiroaki Korekane,Jong Yi Park,Akio Matsumoto,Kazuki Nakajima,Shinji Takamatsu,Kazuaki Ohtsubo,Yasuhide Miyamoto,Shinya Hanashima,Kenji Kanekiyo,Shinobu Kitazume,Yoshiki Yamaguchi,Ichiro Matsuo,Naoyuki Taniguchi +12 more
TL;DR: The existence of an endogenous inhibitory factor for GnT-IX that functions as a key regulator for Gnt-IX enzymatic activity in Neuro2a (N2a) cells is demonstrated and a novel regulatory system for the cellular glycosylation process is proposed.
Journal ArticleDOI
Effects of Multiple Injection of Bone Marrow Mononuclear Cells on Spinal Cord Injury of Rats.
Kenji Kanekiyo,Norihiko Nakano,Tamami Homma,Yoshihiro Yamada,Masahiro Tamachi,Yoshihisa Suzuki,Masanori Fukushima,Fukuki Saito,Chizuka Ide +8 more
TL;DR: The results showed that although tissue recoveries were similar between single and multiple injection, the multiple injection of BMNCs was more beneficial for locomotor improvement than single injection for the treatment of SCI.
Journal ArticleDOI
Cell transplantation for the treatment of spinal cord injury - bone marrow stromal cells and choroid plexus epithelial cells.
TL;DR: It is suggested that BMSCs and CPECs secret neurotrophic factors that promote tissue repair of the spinal cord, including axonal regeneration and reduced cavity formation, promotes "intrinsic" ability ofThe spinal cord to regenerate.