K
Kenneth S. Campbell
Researcher at University of Kentucky
Publications - 147
Citations - 4324
Kenneth S. Campbell is an academic researcher from University of Kentucky. The author has contributed to research in topics: Myosin & Medicine. The author has an hindex of 32, co-authored 112 publications receiving 3538 citations. Previous affiliations of Kenneth S. Campbell include University of Birmingham & University of Wisconsin-Madison.
Papers
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Journal ArticleDOI
Closing the therapeutic loop.
Kenneth S. Campbell,Christopher M. Yengo,Lik Chuan Lee,John Kotter,Vincent L. Sorrell,Maya Guglin,Jonathan F. Wenk +6 more
Posted ContentDOI
FiberSim: a flexible open-source model of myofilament-level contraction
TL;DR: FiberSim as mentioned in this paper is an open-source spatially-explicit computer model that simulates myofilament level mechanics and can predict how modulating the function of a sarcomeric protein will impact contractility.
Journal ArticleDOI
Building biorepositories in the midst of a pandemic
Jennifer A. Croker,Robin Patel,Kenneth S. Campbell,Marietta Barton-Baxter,Shannon M. Wallet,Gary S. Firestein,Robert P. Kimberly,Olivier Elemento +7 more
TL;DR: Feedback revealed a major shift in biorepository model, specimen-acquisition and consent process from a combination of investigator-initiated and institutional protocols to an enterprise-serving strategy during the COVID-19 pandemic.
Journal ArticleDOI
Response to Bianco et al.: Interaction Forces between F-actin and Titin PEVK Domain Measured with Optical Tweezers
Kenneth S. Campbell,Martin Lakie +1 more
TL;DR: It is suggested that the thixotropic properties of striated muscles in vivo are more likely to reflect dynamic changes in the proportion of myosin cross-bridges bound between the myofilaments.
Journal ArticleDOI
No Difference in Myosin Kinetics and Spatial Distribution of the Lever Arm in the Left and Right Ventricles of Human Hearts.
Divya Duggal,Sebastian Requena,Janhavi Nagwekar,Sangram Raut,Ryan Rich,Hriday K. Das,Vipulkumar Patel,Vipulkumar Patel,Ignacy Gryczynski,Rafal Fudala,Zygmunt Gryczynski,Cheavar A. Blair,Kenneth S. Campbell,Julian Borejdo +13 more
TL;DR: The results suggest that there is no difference in the way myosin interacts with thin filaments in myocytes of failing hearts, and suggests that the difference in pumping efficiencies are caused by interactions between muscle proteins other than myOSin or that they are purely morphological.