Kıvılcım Kılıç

TL;DR: Capillary pericytes do express α-SMA, which rapidly depolymerizes during tissue fixation thus evading detection by immunolabeling, and the existence of a smaller pool of α- SMA in distal capillaryPericytes that is quickly lost by depolyMERization is confirmed.

TL;DR: It is demonstrated that selective activation of cortical excitation and inhibition elicits distinct vascular responses and the vasoconstrictive mechanism is identified as Neuropeptide Y (NPY) acting on Y1 receptors, implying that task-related negative Blood Oxygenation Level Dependent fMRI signals in the cerebral cortex under normal physiological conditions may be mainly driven by the NPY-positive inhibitory neurons.

TL;DR: Optical imaging and manipulation technologies cannot be easily integrated with electrical recordings due to generation of light-induced artifacts, so transparent graphene microelectrode fabrication is reported to achieve artifact-free electrical recordings along with deep 2-photon imaging in vivo.

TL;DR: Rverberation two-photon microscopy enables video-rate multiplane neuroimaging by performing near-instantaneous axial scanning over large depth ranges while maintaining 3D micrometer-scale resolution.

TL;DR: This first systematic analysis of capillary RBC stalls in the brain, enabled by rapid and continuous volumetric imaging of capillaries with OCT-angiography, will lead to future investigations of the potential role of stalling events in cerebral pathologies.