Klaus-Peter Pleissner

TL;DR: The discovery of 287 human host cell genes influencing influenza A virus replication in a genome-wide RNA interference (RNAi) screen is reported, and SON DNA binding protein was found to be important for normal trafficking of influenza virions to late endosomes early in infection.

TL;DR: Five approaches presented here resulted in the detection of disease‐associated proteins, including Calgranulin B was upregulated in colorectal cancer, and hepatoma‐derived aldose reductase‐like protein was reexpressed in a rat model during hepatocarcinogenesis.

TL;DR: The use of microarrays can reveal patterns of gene gain or loss when examined within a phylogenetic context that is based on sequences of core genes within Helicobacter pylori.

TL;DR: Genome-wide RNAi screening revealed numerous host factors involved in H. pylori-, but not IL-1β- and TNF-α-dependent NF-κB regulation, highlighting the ALPK1-TIFA axis as a core innate immune pathway.

TL;DR: The present data set provides a valuable resource for selection of candidate vaccine antigens and suggests that proteome data sets may be used to identify regulatory elements in mRNAs.