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Konstantinos Spargias
Researcher at Valve Corporation
Publications - 72
Citations - 2111
Konstantinos Spargias is an academic researcher from Valve Corporation. The author has contributed to research in topics: Aortic valve & Mitral regurgitation. The author has an hindex of 19, co-authored 69 publications receiving 1555 citations. Previous affiliations of Konstantinos Spargias include Yahoo!.
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Journal ArticleDOI
Ascorbic Acid Prevents Contrast-Mediated Nephropathy in Patients With Renal Dysfunction Undergoing Coronary Angiography or Intervention
Konstantinos Spargias,Elias Alexopoulos,Stamatis Kyrzopoulos,Panayiotis Iacovis,Darren C. Greenwood,Athanassios Manginas,Vassilis Voudris,Gregory Pavlides,Christopher E. Buller,Dimitrios Th. Kremastinos,Dennis V. Cokkinos +10 more
TL;DR: Prophylactic oral administration of ascorbic acid may protect against contrast-mediated nephropathy in high-risk patients undergoing a coronary procedure.
Journal ArticleDOI
Early Experience With New Transcatheter Mitral Valve Replacement
Vinayak Bapat,Vivek Rajagopal,Christopher Meduri,R. Saeid Farivar,Antony Walton,Stephen J. Duffy,Robert Gooley,Aubrey Almeida,Michael J. Reardon,Neal S. Kleiman,Konstantinos Spargias,Stratis Pattakos,Martin K.C. Ng,Michael K. Wilson,David H. Adams,Martin B. Leon,Michael J. Mack,Sharla Chenoweth,Paul Sorajja,Intrepid Global Pilot Study Investigators +19 more
TL;DR: TMVR with the valve was feasible in a study group at high or extreme risk for conventional mitral valve replacement, and these results inform trial design of TMVR in lower-risk patients with severe mitral valves regurgitation.
Journal ArticleDOI
Compassionate use of the PASCAL transcatheter mitral valve repair system for patients with severe mitral regurgitation: a multicentre, prospective, observational, first-in-man study
Fabien Praz,Konstantinos Spargias,Michael Chrissoheris,Lutz Büllesfeld,Georg Nickenig,Florian Deuschl,Robert Schueler,Neil Fam,Robert Moss,Moody Makar,Robert H. Boone,Jeremy Edwards,Aris Moschovitis,Saibal Kar,John G. Webb,Ulrich Schäfer,Ted Feldman,Stephan Windecker +17 more
TL;DR: This study establishes feasibility of the Edwards PASCAL TMVr system with a high rate of technical success and reduction of mitral regurgitation severity, and further research is needed on procedural and long-term clinical outcomes.
Journal ArticleDOI
Clinical Outcomes With a Repositionable Self-Expanding Transcatheter Aortic Valve Prosthesis: The International FORWARD Study.
Eberhard Grube,Nicolas M. van Mieghem,Sabine Bleiziffer,Thomas Modine,Johan Bosmans,Ganesh Manoharan,Axel Linke,Werner Scholtz,Didier Tchetche,Ariel Finkelstein,Ramiro Trillo,Claudia Fiorina,Antony Walton,Christopher J Malkin,Jae K. Oh,Hongyan Qiao,Stephan Windecker,Nicolas M. Van Mieghem,Ajay Sinhal,Robert Gooley,Tony Walton,Gerald Yong,John G. Webb,Michael W.A. Chu,Sam Radhakrishnan,Antonio Dager,Marian Branny,Emmanuel Teiger,Bernard Chevalier,Dominique Himbert,Gerhard Schymik,Tobias Zeus,Christoph J Jensen,Tienush Rassaf,Stephan Fichtlscherer,Georg Nickenig,Jörg Kempfert,Axel Harnath,Ruth H. Strasser,Christian Frerker,Konstantinos Spargias,Béla Merkely,Corrado Tamburino,Antonio Colombo,Anna Sonia Petronio,Francesco Bedogni,Giovanni Amoroso,Jan van der Heijden,Pim A.L. Tonino,Pedro Echeverria Beliz,Adam Witkowski,Vasco Gama Ribeiro,Moheeb Al Abdullah,Hellmuth Weich,José María Hernández García,César Morís,Anders Jönsson,Saib Khogali,David Hildick-Smith +58 more
TL;DR: TAVR using the next-generation THV is clinically safe and effective for treating older patients with severe AS at increased operative risk.
Journal ArticleDOI
Transcatheter Valve Repair for Patients With Mitral Regurgitation: 30-Day Results of the CLASP Study
D. Scott Lim,Saibal Kar,Konstantinos Spargias,Robert Kipperman,William W. O'Neill,Martin K.C. Ng,Neil Fam,Darren L. Walters,John G. Webb,Robert L. Smith,Michael Rinaldi,Azeem Latib,Gideon Cohen,Ulrich Schäfer,Leo Marcoff,Prashanthi Vandrangi,Patrick Verta,Ted Feldman +17 more
TL;DR: In this article, the authors report the procedural and 30-day results of the PASCAL Transcatheter Valve Repair System (Edwards Lifesciences, Irvine, California) in patients with mitral regurgitation (MR) enrolled in the multicenter, prospective, single-arm CLASP study.