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Kozo Kaibuchi

Researcher at Nagoya University

Publications -  508
Citations -  63012

Kozo Kaibuchi is an academic researcher from Nagoya University. The author has contributed to research in topics: Rho-associated protein kinase & Phosphorylation. The author has an hindex of 129, co-authored 493 publications receiving 60461 citations. Previous affiliations of Kozo Kaibuchi include Nara Institute of Science and Technology & Indiana University – Purdue University Indianapolis.

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Transactivation of the TPA-responsive element by the oncogenic C-erbB-2 protein is partly mediated by protein kinase C.

TL;DR: Results indicate that protein kinase C is partly involved in oncogenic signalling of the active c-erbB-2 protein that leads to Jun/Fos-mediated transcriptional activation in nuclei.
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NMDA receptor antagonist prevents cell death in the hippocampal dentate gyrus induced by hyponatremia accompanying adrenal insufficiency in rats.

TL;DR: Results demonstrated that in adrenal insufficient rats, hyponatremia was associated with apoptosis in the DG, and that memantine prevented the apoptosis and improved cell function, and imply the importance of assessing the possibility of neurological impairments after treatment with CORT in patients with moderate or severe hypon atremia accompanying adrenal insufficiency.
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Striatal TRPV1 activation by acetaminophen ameliorates dopamine D2 receptor antagonist-induced orofacial dyskinesia.

TL;DR: In this paper, a 21-day treatment with haloperidol increased the number of vacuous chewing movements (VCMs) in rats, an effect that was inhibited by either oral acetaminophen treatment or intracerebroventricular injection of N-(4-hydroxyphenyl)-arachidonylamide (AM404) which acts as an activator of the transient receptor potential vanilloid 1 (TRPV1).
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SOCS3-microtubule interaction via CLIP-170 and CLASP2 is critical for modulation of endothelial inflammation and lung injury.

TL;DR: In this article, the authors investigated the role of the protein suppressor of cytokine signaling-3 (SOCS3) in modulation of lung EC barrier dysfunction caused by bacterial pathogens.
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Phosphoproteomic Analysis Using the WW and FHA Domains as Biological Filters

TL;DR: The Kinase-Oriented Substrate Screening (KiOSS) method, which used phosphoprotein-binding domains, showed that WW and FHA are applicable and useful for the identification of novel phospho-substrates for kinases and can therefore be used as biological filters for comprehensive phosphoproteome analysis.