L
Lanny Hsieh
Researcher at University of California, Irvine
Publications - 12
Citations - 7059
Lanny Hsieh is an academic researcher from University of California, Irvine. The author has contributed to research in topics: Medicine & Epitope. The author has an hindex of 5, co-authored 10 publications receiving 4051 citations. Previous affiliations of Lanny Hsieh include University of California.
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Journal ArticleDOI
Remdesivir for the Treatment of Covid-19 - Final Report.
John H. Beigel,Kay M. Tomashek,Lori E. Dodd,Aneesh K. Mehta,Barry S. Zingman,Andre C. Kalil,Elizabeth L. Hohmann,Helen Y. Chu,Annie Luetkemeyer,Susan Kline,Diego Lopez de Castilla,Robert W. Finberg,Kerry Dierberg,Victor F. Tapson,Lanny Hsieh,Thomas F. Patterson,Roger Paredes,Daniel A. Sweeney,William R. Short,Giota Touloumi,David Chien Lye,Norio Ohmagari,Myoung-don Oh,Guillermo M. Ruiz-Palacios,Thomas Benfield,Gerd Fätkenheuer,Mark G. Kortepeter,Robert L. Atmar,C. Buddy Creech,JD Lundgren,Abdel G. Babiker,Sarah Pett,James D. Neaton,Timothy Burgess,Tyler Bonnett,Michelle Green,Mat Makowski,Anu Osinusi,Seema U Nayak,H. Clifford Lane +39 more
TL;DR: The data show that remdesivir was superior to placebo in shortening the time to recovery in adults who were hospitalized with Covid-19 and had evidence of lower respiratory tract infection.
Journal ArticleDOI
Baricitinib plus Remdesivir for Hospitalized Adults with Covid-19.
Andre C. Kalil,Thomas F. Patterson,Aneesh K. Mehta,Kay M. Tomashek,Cameron R. Wolfe,Varduhi Ghazaryan,Vincent C. Marconi,Guillermo M. Ruiz-Palacios,Lanny Hsieh,Susan Kline,Victor F. Tapson,Nicole M. Iovine,Mamta K. Jain,Daniel A. Sweeney,Hana M. El Sahly,Angela Branche,Justino Regalado Pineda,David C. Lye,Uriel Sandkovsky,Anne F Luetkemeyer,Stuart H. Cohen,Robert W. Finberg,Patrick E. H. Jackson,Babafemi Taiwo,Catharine I. Paules,Henry Arguinchona,Nathaniel B. Erdmann,Neera Ahuja,Maria G. Frank,Myoung Don Oh,Eu-Suk Kim,Seow Y Tan,Richard A. Mularski,Henrik Nielsen,Philip O Ponce,Barbara S. Taylor,LuAnn Larson,Nadine Rouphael,Youssef Saklawi,Valeria D Cantos,Emily R Ko,John J. Engemann,Alpesh Amin,Miki Watanabe,Joanne Billings,Marie-Carmelle Elie,Richard T. Davey,Timothy Burgess,Jennifer Ferreira,Michelle Green,Mat Makowski,Anabela Cardoso,Stephanie de Bono,Tyler Bonnett,Michael A. Proschan,Gregory A. Deye,Walla Dempsey,Seema U Nayak,Lori E. Dodd,John H. Beigel +59 more
TL;DR: Baricitinib plus remdesivir was superior to remdes Vivir alone in reducing recovery time and accelerating improvement in clinical status among patients with Covid-19, notably among those receiving high-flow oxygen or noninvasive ventilation.
Journal ArticleDOI
A Case of Novel Coronavirus Disease 19 in a Chronic Hemodialysis Patient Presenting with Gastroenteritis and Developing Severe Pulmonary Disease.
Antoney Ferrey,Grace Choi,Ramy M Hanna,Yongen Chang,Ekamol Tantisattamo,Kaushik Ivaturi,Elisa Park,Lawrence Nguyen,Brian Wang,Sam Tonthat,Connie M. Rhee,Uttam Reddy,Wei Ling Lau,Susan S. Huang,Shruti K. Gohil,Alpesh Amin,Lanny Hsieh,Timmy Cheng,Richard A Lee,Kamyar Kalantar-Zadeh +19 more
TL;DR: This case is unique in its atypical initial presentation and highlights the importance of early testing in patients with chronic kidney disease, particularly patients with end-stage renal disease who are dialysis dependent.
Journal ArticleDOI
Baricitinib versus dexamethasone for adults hospitalised with COVID-19 (ACTT-4): a randomised, double-blind, double placebo-controlled trial
Cameron R. Wolfe,Kay M. Tomashek,Thomas L. Patterson,Carlos A. Gomez,Vincent C. Marconi,M. Jain,Otto O. Yang,Catharine I. Paules,Guillermo Miguel Ruiz Palacios,Robert Grossberg,Michelle Harkins,Richard A. Mularski,Nathaniel B. Erdmann,Uriel Sandkovsky,Eyad Almasri,Justino Regalado Pineda,Alexandra W. Dretler,Diego Lopez de Castilla,Angela Branche,Pauline K. Park,Aneesh K. Mehta,William R. Short,Susan McLellan,Susan Kline,Nicole M. Iovine,Hana M. El Sahly,Sarah B Doernberg,Myoung Don Oh,Nikhil Huprikar,Elizabeth L. Hohmann,Colleen F. Kelley,Mark Holodniy,Eu Suk Kim,Daniel A. Sweeney,Robert W. Finberg,Kevin A. Grimes,Ryan C. Maves,Emily R Ko,John J. Engemann,Barbara S. Taylor,Philip O Ponce,LuAnn Larson,Dante P. Melendez,Allan M. Seibert,Nadine Rouphael,Joslyn K. Strebe,Jesse L. Clark,Kathleen G. Julian,Alfredo Ponce de León,Anabela Cardoso,Stephanie de Bono,Robert L. Atmar,Anuradha Ganesan,Jennifer L. Ferreira,Michelle Green,Mat Makowski,Tyler Bonnett,Tatiana Beresnev,Varduhi Ghazaryan,Walla Dempsey,Seema U Nayak,Lori E. Dodd,John H. Beigel,Andre C. Kalil,L. Wahid,Emmanuel B. Walter,Akhila Belur,Grace Dreyer,Janet E. Patterson,Jason Bowling,D. O. Dixon,Angela L. Hewlett,Robert Odrobina,Jakrapun Pupaibool,S Mocherla,Suzana Lazarte,Meilani Cayabyab,Rezhan Hussein,Reshma Golamari,Kaleigh L. Krill,Sandra Rajme,Paul F. Riska,Barry S. Zingman,Gregory J. Mertz,Nestor Sosa,Paul A. Goepfert,Mezgebe Berhe,Emma Dishner,Mohamed Fayed,K. Hubel,José Arturo Martínez-Orozco,Nora Bautista Felix,Sammy T. Elmor,Amer Bechnak,Youssef Saklawi,Jason W. Van Winkle,Diego Fernando Zea,Maryrose Laguio-Vila,Edward E. Walsh,Ann R. Falsey,Karen L Carvajal,Robert C. Hyzy,Sinan Hanna,Norman Olbrich,Jessica Traenkner,Colleen S. Kraft,Pablo Tebas,Jillian Baron,Corri B. Levine,J. J. Nock,Joanne Billings,Hyun Kim,Marie-Carmelle Elie-Turenne,Jennifer A. Whitaker,Anne F Luetkemeyer,J. Dwyer,E. Bainbridge,Pyoeng Gyun Choe,Chang Kyung Kang,Nikolaus Jilg,Valeria D Cantos,Divya R. Bhamidipati,Srinivasa Nithin Gopalsamy,Aarthi Chary,Jongtak Jung,Kyoung Ho Song,Hong Bin Kim,Constance A. Benson,Kim McConnell,Jennifer P. Wang,Mireya Wessolossky,K.Y. Ayala Perez,Taryn A Eubank,Catherine M. Berjohn,Gregory Utz,Patrick E. H. Jackson,Taison D. Bell,Heather M. Haughey,Abeer Moanna,Sushma K. Cribbs,Telisha Harrison,C. Colombo,Christina Schofield,Rhonda E Colombo,Victor F. Tapson,Jonathan Grein,Fayyaz S. Sutterwala,Dilek Ince,Patricia L. Winokur,Monica Fung,Hannah Jang,David L. Wyles,Maria G. Frank,Ellen Sarcone,Henry Neumann,Anand Viswanathan,Sarah Hochman,Mark J. Mulligan,Benjamin J. Eckhardt,Ellie Carmody,Neera Ahuja,Kari C. Nadeau,David Svec,Jeffrey Macaraeg,Lee Alan Morrow,David Quimby,Mary T. Bessesen,Lindsay Nicholson,Jill C. Adams,Princy Kumar,Allison A. Lambert,Henry Arguinchona,Radica Z. Alicic,Sho Saito,Norio Ohmagari,Ayako Mikami,David Chien Lye,Tau Hong Lee,Po Ying Chia,Lanny Hsieh,Alpesh Amin,Miki Watanabe,Keith A. Candiotti,J. G. D. Castro,Maria A. Antor,Tida K. Lee,Tahaniyat Lalani,Richard M. Nowak,Andrea Wendrow,Scott Borgetti,Sarah L. George,Daniel F. Hoft,James D. Brien,Stuart H. Cohen,George Richard Thompson,Melony Chakrabarty,Faheem W. Guirgis,Richard T. Davey,Jocelyn Voell,Jeffrey R Strich,David A Lindholm,Katrin Mende,Trevor Wellington,Rekha R. Rapaka,Jennifer Husson,Andrea R. Levine,Seow Yen Tan,Huma Shafi,Jaime Chien,David C. Hostler,Jordanna Hostler,Brian Shahan,David Adams,Anu Osinusi,Huyen Cao,Timothy Burgess,Julia S. Rozman,Kevin K. Chung,C. Nieuwoudt,Jill El-Khorazaty,Heather Hill,Stephanie Pettibone,Nikki Gettinger,T. Engel,Teri Lewis,Jing Wang,Gregory Deye,Effie Y.H. Nomicos,Rhonda Pikaart-Tautges,Mohamed Elsafy,Robert Jurao,Hyung Chan Koo,Michael A. Proschan,Tammy Yokum,Janice Arega,Ruth H. Florese +235 more
TL;DR: The primary outcome was the difference in mechanical ventilation-free survival by day 29 between the two treatment groups in the modified intention-to-treat population.
Journal ArticleDOI
Genome-Wide B Cell, CD4 + , and CD8 + T Cell Epitopes That Are Highly Conserved between Human and Animal Coronaviruses, Identified from SARS-CoV-2 as Targets for Preemptive Pan-Coronavirus Vaccines.
Swayam Prakash,Ruchi Srivastava,Pierre-Gregoire A Coulon,Nisha R Dhanushkodi,Aziz Alami Chentoufi,Delia F. Tifrea,Robert Edwards,Cesar Figueroa,Sebastian D. Schubl,Lanny Hsieh,Michael J. Buchmeier,Mohammed Bouziane,Anthony B. Nesburn,Baruch D. Kuppermann,Lbachir BenMohamed +14 more
TL;DR: In this paper, using several immunoinformatics and sequence alignment approaches, the authors identified several human B cell and CD4+ and CD8+ T cell epitopes that are highly conserved in more than 81,000 SARS-CoV-2 genome sequences.