Lars Ährlund-Richter

TL;DR: It is shown that pluripotent stem cells can be derived from the late epiblast layer of post-implantation mouse and rat embryos using chemically defined, activin-containing culture medium that is sufficient for long-term maintenance of human embryonic stem cells.

TL;DR: It is concluded that hESC lines can be successfully derived using SR medium and postnatal human fibroblasts as feeder cells, a step toward xeno‐free conditions and facilitates the use of these cells in transplantation.

TL;DR: It is shown that human iPSCs rely on activin/nodal signaling to control Nanog expression and thereby maintain pluripotency, thus revealing their mechanistic similarity to human ESCs and showing that these pluripotent cell types are functionally equivalent.

TL;DR: A functional adaptation of a HESC line, HS181, towards a decreased dependence of extra cellular matrix (ECM) for in vitro survival, that is for growth directly onto a plastic surface, is reported.

TL;DR: A significant difference in phenotype between ES cells of the horse and those of the mouse and human is indicated.