H
Heli Skottman
Researcher at University of Tampere
Publications - 137
Citations - 5775
Heli Skottman is an academic researcher from University of Tampere. The author has contributed to research in topics: Embryonic stem cell & Stem cell. The author has an hindex of 41, co-authored 124 publications receiving 4996 citations. Previous affiliations of Heli Skottman include Karolinska University Hospital & Åbo Akademi University.
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Screening ethnically diverse human embryonic stem cells identifies a chromosome 20 minimal amplicon conferring growth advantage
Katherine Amps,Peter W. Andrews,George Anyfantis,Lyle Armstrong,Stuart Avery,Hossein Baharvand,Julie C. Baker,Duncan Baker,Maria D. Barbadillo Muñoz,Stephen J. Beil,Nissim Benvenisty,Dalit Ben-Yosef,Juan Carlos Biancotti,Alexis Bosman,Romulo M. Brena,Daniel R. Brison,Gunilla Caisander,Marãa V. Camarasa,Jieming Chen,Eric Chiao,Young Min Choi,Andre Choo,D.M. Collins,Alan Colman,Jeremy M. Crook,George Q. Daley,Anne Dalton,Paul A. De Sousa,Chris Denning,J.M. Downie,Petr Dvorak,Karen Dyer Montgomery,Anis Feki,Angela Ford,Victoria Fox,Ana Maria Fraga,Tzvia Frumkin,Lin Ge,Paul J. Gokhale,Tamar Golan-Lev,Hamid Gourabi,Michal Gropp,Lu GuangXiu,Aleš Hampl,Katie Harron,Lyn Healy,Wishva Herath,Frida Holm,Outi Hovatta,Johan Hyllner,Maneesha S. Inamdar,Astrid K. Irwanto,Tetsuya Ishii,Marisa Jaconi,Ying Jin,Susan J. Kimber,Sergey Kiselev,Barbara B. Knowles,Oded Kopper,Valeri Kukharenko,Anver Kuliev,Maria A. Lagarkova,Peter W. Laird,Majlinda Lako,Andrew L. Laslett,Neta Lavon,Dong Ryul Lee,Jeoung Eun Lee,Chunliang Li,Linda S. Lim,Tenneille Ludwig,Yu Ma,Edna Maltby,Ileana Mateizel,Yoav Mayshar,Maria Mileikovsky,Stephen L. Minger,Takamichi Miyazaki,Shin Yong Moon,Harry Moore,Christine L. Mummery,Andras Nagy,Norio Nakatsuji,Kavita Narwani,Steve Oh,Sun Kyung Oh,Cia Olson,Timo Otonkoski,Fei Pan,In-Hyun Park,Steve Pells,Martin F. Pera,Lygia da Veiga Pereira,Ouyang Qi,Grace Selva Raj,Benjamin Reubinoff,Alan Robins,Paul Robson,Janet Rossant,Ghasem Hosseini Salekdeh,Thomas C. Schulz,Karen Sermon,Jameelah Sheik Mohamed,Hui Shen,Eric S Sherrer,Kuldip S. Sidhu,Shirani Sivarajah,Heli Skottman,Claudia Spits,Glyn Stacey,Raimund Strehl,Nick Strelchenko,Hirofumi Suemori,Bowen Sun,Riitta Suuronen,Kazutoshi Takahashi,Timo Tuuri,Parvathy Venu,Yuri Verlinsky,Dorien Ward-van Oostwaard,Daniel J. Weisenberger,Yue Wu,Shinya Yamanaka,Lorraine E. Young,Qi Zhou +124 more
TL;DR: Of these genes, BCL2L1 is a strong candidate for driving culture adaptation of ES cells, and single-nucleotide polymorphism analysis revealed that they included representatives of most major ethnic groups.
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Derivation of Human Embryonic Stem Cell Lines in Serum Replacement Medium Using Postnatal Human Fibroblasts as Feeder Cells
José Inzunza,Karin Gertow,Marie A. Strömberg,Eija Matilainen,E. Blennow,Heli Skottman,Susanne Wolbank,Lars Ährlund-Richter,Outi Hovatta +8 more
TL;DR: It is concluded that hESC lines can be successfully derived using SR medium and postnatal human fibroblasts as feeder cells, a step toward xeno‐free conditions and facilitates the use of these cells in transplantation.
Journal ArticleDOI
Good manufacturing practice and clinical-grade human embryonic stem cell lines.
TL;DR: Human embryonic stem cell (hESC) lines, after directed differentiation, hold the greatest potential for cell transplantation treatment in many severe diseases, and GMP-quality xeno-free hESC lines could be established today.
Journal ArticleDOI
Human stem cell based corneal tissue mimicking structures using laser-assisted 3D bioprinting and functional bioinks.
Anni Sorkio,Lothar Koch,Laura Koivusalo,Andrea Deiwick,Susanna Miettinen,Boris N. Chichkov,Heli Skottman +6 more
TL;DR: This is the first study to demonstrate the feasibility of 3D LaBP for corneal applications using human stem cells and successful fabrication of layered 3D bioprinted tissues mimicking the structure of the native cornea-mimicking tissues.
Journal ArticleDOI
Testing of nine different xeno-free culture media for human embryonic stem cell cultures
Kristiina Rajala,Heidi Hakala,Sarita Panula,Suvi Aivio,Harri Pihlajamäki,Riitta Suuronen,Outi Hovatta,Outi Hovatta,Heli Skottman +8 more
TL;DR: None of the studied xeno-free media was able to maintain the undifferentiated growth of hESC and the medium containing 20% human serum was found to sustain undifferentiate h ESC proliferation to some extent, yet was inferior to the conventional ko-SR-containing medium.