L
Laurence Kessler
Researcher at University of Strasbourg
Publications - 72
Citations - 1509
Laurence Kessler is an academic researcher from University of Strasbourg. The author has contributed to research in topics: Transplantation & Islet. The author has an hindex of 20, co-authored 72 publications receiving 1254 citations.
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Journal ArticleDOI
Islet transplantation versus insulin therapy in patients with type 1 diabetes with severe hypoglycaemia or poorly controlled glycaemia after kidney transplantation (TRIMECO): a multicentre, randomised controlled trial
Sandrine Lablanche,Sandrine Lablanche,Marie-Christine Vantyghem,Laurence Kessler,Anne Wojtusciszyn,Sophie Borot,C. Thivolet,Sophie Girerd,Domenico Bosco,Jean-Luc Bosson,Cyrille Colin,Cyrille Colin,Rachel Tetaz,Sophie Logerot,Julie Kerr-Conte,Eric Renard,Alfred Penfornis,Emmanuel Morelon,Fanny Buron,Kristina Skaare,Gwen Grguric,Gwen Grguric,Coralie Camillo-Brault,Coralie Camillo-Brault,Harald Egelhofer,Kanza Benomar,Lionel Badet,Thierry Berney,François Pattou,Pierre-Yves Benhamou,Pierre-Yves Benhamou,Paolo Malvezzi,Igor Tauveron,Béatrice Roche,Christian Noel,Luc Frimat,Bruno Guerci,Nadine Pernin,Anaïck Moisan,Virginie Persoons,Rimed Ezzouaoui,Valery Gmyr,Frédéric Thony,Yvan Bricault,Mathieu Rodière,Christian Sengel,M. Greget,Iulian Enescu,Marc Hazzan,R. Caiazzo,Fanelly Torres,Kristel Le Mapihan,Violetta Raverdy,Marie-Ange Pierredon,Pierre-Jean Valette,Arnaud Muller,Jean Champagnac,Lucy Chaillous,Jacques Dantal,Pierre Cattan,Jean-Pierre Riveline,François Moreau,Philippe Baltzinger,Thibault Bahoune +63 more
TL;DR: For the indications assessed in this study, islet transplantation effectively improves metabolic outcomes and seems to be a valid option for patients with severe, unstable type 1 diabetes who are not responding to intensive medical treatments.
Journal ArticleDOI
Influence of VEGF on the viability of encapsulated pancreatic rat islets after transplantation in diabetic mice.
Séverine Sigrist,A. Mechine-Neuville,K. Mandes,V. Calenda,S Braun,Gilbert Legeay,J.-P. Bellocq,Michel Pinget,Laurence Kessler +8 more
TL;DR: VEGF increased the viability of engrafted encapsulated islets, increasing the duration of a normalized glycemia in diabetic mice following transplantation, and local adjunction of VEGF may improve the clinical outcome of islet transplantation.
Journal ArticleDOI
Early assessment of glucose abnormalities during continuous glucose monitoring associated with lung function impairment in cystic fibrosis patients.
A. Leclercq,B. Gauthier,V. Rosner,Laurence Weiss,François Moreau,Andrei Alexandru Constantinescu,Romain Kessler,Laurence Kessler +7 more
TL;DR: CGM reveals early abnormalities of glucose tolerance that remain undiagnosed by OGTT screening and are associated with worse lung function and a higher prevalence of P. aeruginosa colonization in patients with CF.
Journal ArticleDOI
Comparison of microbiological results of needle puncture vs. superficial swab in infected diabetic foot ulcer with osteomyelitis
Laurence Kessler,Y. Piemont,F. Ortega,O Lesens,C. Boeri,C. Averous,R. Meyer,Y. Hansmann,D. Christmann,J. Gaudias,Michel Pinget +10 more
TL;DR: Two methods for the bacteriological diagnosis of osteomyelitis related to diabetic foot ulcer are studied: needle puncture performed across normal skin surrounding the foot ulcers and superficial swabbing of the ulcer.
Journal ArticleDOI
Reduction of Blood Glucose Variability in Type 1 Diabetic Patients Treated By Pancreatic Islet Transplantation Interest of continuous glucose monitoring
Laurence Kessler,Raphael Passemard,Jose Oberholzer,Pierre-Yves Benhamou,Pascal Alain Robert Bucher,Christian Toso,Pierre Meyer,Alfred Penfornis,Lionel Badet,Philippe Wolf,Cyrille Colin,Philippe Morel,Michel Pinget +12 more
TL;DR: Use of subcutaneous CGMS confirms that islet transplantation can be as efficient as pancreas transplantation in restoring good metabolic control and reducing blood glucose variability.