M
Marie-Christine Vantyghem
Researcher at French Institute of Health and Medical Research
Publications - 261
Citations - 7514
Marie-Christine Vantyghem is an academic researcher from French Institute of Health and Medical Research. The author has contributed to research in topics: Transplantation & Islet. The author has an hindex of 40, co-authored 234 publications receiving 6362 citations. Previous affiliations of Marie-Christine Vantyghem include United States Naval Academy & Lille University of Science and Technology.
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Journal ArticleDOI
Improvement in outcomes of clinical islet transplantation: 1999-2010.
Franca B. Barton,Michael R. Rickels,Rodolfo Alejandro,Bernhard J. Hering,Stephen Wease,Bashoo Naziruddin,Jose Oberholzer,Jon S. Odorico,Marc R. Garfinkel,Marlon F. Levy,François Pattou,Thierry Berney,Antonio Secchi,Shari Messinger,Peter A. Senior,Paola Maffi,Andrew M. Posselt,Peter G. Stock,Dixon B. Kaufman,Xunrong Luo,Fouad Kandeel,Enrico Cagliero,Nicole A. Turgeon,Piotr Witkowski,Ali Naji,Philip J. O'Connell,Carla J. Greenbaum,Yogish C. Kudva,Kenneth L. Brayman,Meredith J. Aull,Christian P. Larsen,Thomas W.H. Kay,Luis A. Fernandez,Marie-Christine Vantyghem,Melena D. Bellin,A. M. James Shapiro +35 more
TL;DR: The CITR shows improvement in primary efficacy and safety outcomes of islet transplantation in recipients who received transplants in 2007–2010 compared with those in 1999–2006, with fewer islet infusions and adverse events per recipient.
Journal ArticleDOI
Assessment of the Severity of Hypoglycemia and Glycemic Lability in Type 1 Diabetic Subjects Undergoing Islet Transplantation
Edmond A. Ryan,Tami Shandro,Kristy Green,Breay W. Paty,Peter A. Senior,David L. Bigam,A. M. James Shapiro,Marie-Christine Vantyghem +7 more
TL;DR: The HYPO score and LI provide measures of the extent of problems with hypoglycemia and glycemic lability, respectively, complement the clinical assessment of the problems with glucose control before islet transplantation, and will allow comparison of selection of subjects for transplants between centers.
Journal ArticleDOI
Ketoconazole in Cushing's disease: is it worth a try?
Frederic Castinetti,Laurence Guignat,Pauline Giraud,M. Muller,Peter Kamenicky,Delphine Drui,Philippe Caron,Fiorina Luca,Bruno Donadille,Marie-Christine Vantyghem,Hélène Bihan,Brigitte Delemer,Gérald Raverot,Emmanuelle Motte,Melanie Philippon,Isabelle Morange,Bernard Conte-Devolx,Laurent Quinquis,Monique Martinie,Delphine Vezzosi,Maëlle Le Bras,Camille Baudry,Sophie Christin-Maitre,Bernard Goichot,Philippe Chanson,Jacques Young,Olivier Chabre,Antoine Tabarin,Jérôme Bertherat,Thierry Brue +29 more
TL;DR: A French retrospective multicenter study reviewing data from patients treated by ketoconazole as a single agent for Cushing's disease, with the aim of clarifying efficacy and tolerance to better determine the benefit/risk balance.
Journal ArticleDOI
Germ-line mutation analysis in patients with multiple endocrine neoplasia type 1 and related disorders.
Sophie Giraud,Chang X. Zhang,Olga Serova-Sinilnikova,Virginie Wautot,Janine Salandre,Nathalie Buisson,Christine Waterlot,Catherine Bauters,Nicole Porchet,Jean-Pierre Aubert,Philippe Emy,Guillaume Cadiot,Brigitte Delemer,Olivier Chabre,Patricia Niccoli,Frédéric Leprat,Françoise Duron,Brigitte Emperauger,Patrick Cougard,Pierre Goudet,Emile Sarfati,Jean Paul Riou,Sylvie Guichard,Michel Rodier,Alain Meyrier,Philippe Caron,Marie-Christine Vantyghem,Michel Assayag,Jean Louis Peix,Michel Pugeat,Vincent Rohmer,Michel Vallotton,Gilbert M. Lenoir,Patrick Gaudray,Charles Proye,Bernard Conte-Devolx,Philippe Chanson,Yin Y. Shugart,David E. Goldgar,Arnaud Murat,Alain Calender +40 more
TL;DR: A total of 84 families and/or isolated patients with either MEN1 or MEN1-related inherited endocrine tumors were screened for MEN1 germ-line mutations, by heteroduplex and sequence analysis of the MEN1 gene-coding region and untranslated exon 1, and 52 distinct mutations were characterized.
Journal ArticleDOI
Spectrum of Mutations in Gitelman Syndrome
Rosa Vargas-Poussou,Karin Dahan,Diana Kahila,Annabelle Venisse,Eva Riveira-Munoz,Huguette Debaix,Bernard Grisart,Franck Bridoux,Robert J. Unwin,Bruno Moulin,Jean-Philippe Haymann,Marie-Christine Vantyghem,Claire Rigothier,Bertrand Dussol,Michel Godin,Hubert Nivet,Laurence Dubourg,Ivan Tack,Anne-Paule Gimenez-Roqueplo,Pascal Houillier,Anne Blanchard,Olivier Devuyst,Xavier Jeunemaitre +22 more
TL;DR: Gitelman's syndrome (GS) is a rare, autosomal recessive, salt-losing tubulopathy caused by mutations in the SLC12A3 gene, which encodes the thiazide-sensitive NaCl cotransporter.