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Laurent Excoffier

Researcher at University of Bern

Publications -  243
Citations -  90328

Laurent Excoffier is an academic researcher from University of Bern. The author has contributed to research in topics: Population & Coalescent theory. The author has an hindex of 94, co-authored 240 publications receiving 84545 citations. Previous affiliations of Laurent Excoffier include University of Basel & Université de Montréal.

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Journal Article

HLA-DR polymorphism in a Senegalese Mandenka population: DNA oligotyping and population genetics of DRB1 specificities.

TL;DR: Observed high heterozygosity levels in tested populations are compatible with an overdominant model with a small selective advantage for heterozygotes, and a significant positive correlation between genetic and geographic differentiation patterns is shown.
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Detection of convergent genome-wide signals of adaptation to tropical forests in humans

TL;DR: Genetic data was analyzed for outlier markers with an overly large extent of differentiation between populations living in a tropical forest, as compared to genetically related populations living outside the forest in Africa and the Americas, suggesting that Africans and Amerindians may have followed different routes to adapt to similar environmental selective pressures.
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Low levels of mitochondrial DNA variation among central and southern European Esox lucius populations

TL;DR: Low levels of mitochondrial DNA variation were observed among pike Esox lucius populations from major drainage systems of Europe and populations from the Italian peninsula including southern Switzerland were genetically distinct from other samples.
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SPLATCHE3: simulation of serial genetic data under spatially explicit evolutionary scenarios including long-distance dispersal

TL;DR: SPATCHE3 as mentioned in this paper is a framework for simulating genetic data under a variety of spatially explicit evolutionary scenarios, extending previous versions of the SPLATCHE framework, including long-distance migration, spatially and temporally heterogeneous short-scale migrations, alternative hybridization models, simulation of serial samples of genetic data and a large variety of DNA mutation models.