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Carlos Eduardo G. Amorim
Researcher at Columbia University
Publications - 27
Citations - 693
Carlos Eduardo G. Amorim is an academic researcher from Columbia University. The author has contributed to research in topics: Population & Natural selection. The author has an hindex of 12, co-authored 25 publications receiving 502 citations. Previous affiliations of Carlos Eduardo G. Amorim include Coordenadoria de Aperfeiçoamento de Pessoal de Nível Superior & Swiss Institute of Bioinformatics.
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Journal ArticleDOI
Variation in the molecular clock of primates
TL;DR: There is substantial variation in the molecular clock between apes and monkeys and that rates even differ within hominines, and not only the total rate, but also the mutational spectrum, varies among primates, suggesting that events in primate evolution are most reliably dated using CpG transitions.
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Understanding 6th-century barbarian social organization and migration through paleogenomics
Carlos Eduardo G. Amorim,Stefania Vai,Cosimo Posth,Alessandra Modi,István Koncz,Susanne Hakenbeck,Maria Cristina La Rocca,Balázs Gusztáv Mende,Dean Bobo,Walter Pohl,Luisella Pejrani Baricco,Elena Bedini,Paolo Francalacci,Caterina Giostra,Tivadar Vida,Tivadar Vida,Daniel Winger,Uta von Freeden,Silvia Ghirotto,Martina Lari,Guido Barbujani,Johannes Krause,David Caramelli,Patrick J. Geary,Krishna R. Veeramah +24 more
TL;DR: In this paper, the authors obtained ancient genomic DNA from 63 samples from two cemeteries (from Hungary and Northern Italy) that have been previously associated with the Longobards, a barbarian people that ruled large parts of Italy for over 200 years after invading from Pannonia in 568 CE.
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Genetic signature of natural selection in first Americans.
Carlos Eduardo G. Amorim,Kelly Nunes,Diogo Meyer,David Comas,Maria Cátira Bortolini,Francisco M. Salzano,Tábita Hünemeier +6 more
TL;DR: Signs of natural selection at the fatty acid desaturases (FADS) genes are found not only in an Arctic population, as was previously found, but throughout the Americas, suggesting a single and strong adaptive event that occurred in Beringia, before the range expansion of the first Americans within the American continent and Greenland.
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The population genetics of human disease: The case of recessive, lethal mutations
Carlos Eduardo G. Amorim,Carlos Eduardo G. Amorim,Ziyue Gao,Zachary Baker,Jose Francisco Diesel,Yuval B. Simons,Imran S. Haque,Joseph K. Pickrell,Molly Przeworski +8 more
TL;DR: It is argued that the unexpectedly high frequency of disease mutations and the relationship to the mutation rate likely reflect an ascertainment bias: of all the mutations that cause recessive lethal diseases, those that by chance have reached higher frequencies are more likely to have been identified and thus to have be included in this study.
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Evolutionary responses to a constructed niche: Ancient mesoamericans as a model of gene-culture coevolution
Tábita Hünemeier,Carlos Eduardo G. Amorim,Soledad de Azevedo,Verônica Contini,Victor Acuña-Alonzo,Francisco Rothhammer,Francisco Rothhammer,Jean-Michel Dugoujon,Stéphane Mazières,Ramiro Barrantes,María Teresa Villarreal-Molina,Vanessa Rodrigues Paixão-Côrtes,Francisco M. Salzano,Samuel Canizales-Quinteros,Andres Ruiz-Linares,Maria Cátira Bortolini +15 more
TL;DR: The correlation of its frequencies with the archeological data on Zea pollen in Mesoamerica/Central America, the neutral coalescent simulations, and the FST-based natural selection analysis suggest that maize domestication was the driving force in the increase in the frequencies of 230Cys in this region.