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Laurent Excoffier

Researcher at University of Bern

Publications -  243
Citations -  90328

Laurent Excoffier is an academic researcher from University of Bern. The author has contributed to research in topics: Population & Coalescent theory. The author has an hindex of 94, co-authored 240 publications receiving 84545 citations. Previous affiliations of Laurent Excoffier include University of Basel & Université de Montréal.

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Killer whale genomes reveal a complex history of recurrent admixture and vicariance.

TL;DR: This study analyses a global data set of killer whale genomes in a rare attempt to elucidate global population structure in a nonhuman species and underpins that episodic gene flow is ubiquitous in natural populations, and can occur across great distances and after substantial periods of isolation between populations.
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Nuclear DNA polymorphism in a Mandenka population from Senegal: comparison with eight other human populations

TL;DR: A large and ethnically well defined Mandenka sample from Senegal is analysed for 80 nuclear DNA RFLPs, and compared with eight previously studied human populations, suggesting that geography does also affect long range population genetic relationships and is an important factor behind differentiation among human populations.
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Genomic landscape of early ecological speciation initiated by selection on nuptial colour.

TL;DR: It is demonstrated that in the population described, differences in throat colour and breeding have been stable over a decade, but in contrast to North American benthic and limnetic stickleback species, these mating trait differences are not accompanied by divergence in morphology related to feeding, predator defence or swimming performance.
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Mutation load dynamics during environmentally-driven range shifts.

TL;DR: This work uses individual-based simulations and analytical modeling to compare the impact of range expansions and range shifts on genetic diversity and fitness loss, as well as the ability to recover fitness after either a shift or expansion.
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Polygenic Patterns of Adaptive Introgression in Modern Humans Are Mainly Shaped by Response to Pathogens

TL;DR: The results confirm that archaic introgression has facilitated local adaptation, especially in immunity-related and metabolic functions and highlight its involvement in a coordinated response to pathogens out of Africa.