L
Leah C. Wehmas
Researcher at United States Environmental Protection Agency
Publications - 26
Citations - 859
Leah C. Wehmas is an academic researcher from United States Environmental Protection Agency. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 14, co-authored 21 publications receiving 723 citations. Previous affiliations of Leah C. Wehmas include Oregon State University.
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Journal ArticleDOI
Comparative Metal Oxide Nanoparticle Toxicity Using Embryonic Zebrafish
Leah C. Wehmas,Catherine B. Anders,Jordan Chess,Alex Punnoose,Cliff Pereira,Juliet A. Greenwood,Robert L. Tanguay +6 more
TL;DR: Data from agglomerated MO NPs suggests that the elemental composition and dissolution potential are major drivers of toxicity, and exposure to dissolved Zn2+ may be a major contributor to ZnO toxicity.
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Silver nanoparticle toxicity in the embryonic zebrafish is governed by particle dispersion and ionic environment
TL;DR: It is demonstrated that size- and surface coating-dependent toxicity is a result of AgNPs remaining unagglomerated, and thus a critical-design consideration for experiments to offer meaningful evaluations of AgNP toxicity.
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Effects of a glucocorticoid receptor agonist, dexamethasone, on fathead minnow reproduction, growth, and development
Carlie A. LaLone,Daniel L. Villeneuve,Allen W. Olmstead,Elizabeth K. Medlock,Michael D. Kahl,Kathleen M. Jensen,Elizabeth J. Durhan,Elizabeth A. Makynen,Chad A. Blanksma,Jenna E. Cavallin,Linnea M. Thomas,Sara M. Seidl,Sarah Y. Skolness,Leah C. Wehmas,Rodney D. Johnson,Gerald T. Ankley +15 more
TL;DR: Results indicate that nonlethal concentrations of a model glucocorticoid receptor agonist can impair fish reproduction, growth, and development.
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Investigating Alternatives to the fish early-life stage test: A strategy for discovering and annotating adverse outcome pathways for early fish development
Daniel L. Villeneuve,David C. Volz,Michelle R. Embry,Gerald T. Ankley,Scott E. Belanger,Marc Léonard,Kristin Schirmer,Robert L. Tanguay,Lisa Truong,Leah C. Wehmas +9 more
TL;DR: An overall strategy for the discovery and annotation of FELS AOPs was illustrated and key research objectives were defined relative to factors such as current animal-use restrictions in the European Union and increased demands for fish toxicity data in chemical management programs globally.
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Dynamic Nature of Alterations in the Endocrine System of Fathead Minnows Exposed to the Fungicide Prochloraz
Gerald T. Ankley,David C. Bencic,Jenna E. Cavallin,Kathleen M. Jensen,Michael D. Kahl,Elizabeth A. Makynen,Dalma Martinović,Nathaniel D. Mueller,Leah C. Wehmas,Daniel L. Villeneuve +9 more
TL;DR: The adaptability of the HPG axis to chemical stress is demonstrated and the need to consider the dynamic nature of the system when developing approaches to assess potential risks of endocrine-active chemicals is highlighted.