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Leonardo José Tadeu de Araújo

Researcher at Instituto Adolfo Lutz

Publications -  16
Citations -  1196

Leonardo José Tadeu de Araújo is an academic researcher from Instituto Adolfo Lutz. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 4, co-authored 12 publications receiving 536 citations.

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Genomics and epidemiology of the P.1 SARS-CoV-2 lineage in Manaus, Brazil.

Nuno R. Faria, +74 more
- 21 May 2021 - 
TL;DR: In this article, the authors used a two-category dynamical model that integrates genomic and mortality data to estimate that P.1 may be 1.7-to 2.4-fold more transmissible and that previous (non-P.1) infection provides 54 to 79% of the protection against infection with P.
Posted ContentDOI

Genomics and epidemiology of a novel SARS-CoV-2 lineage in Manaus, Brazil

Nuno R. Faria, +74 more
- 03 Mar 2021 - 
TL;DR: In this paper, the emergence and circulation of a new SARS-CoV-2 variant of concern, lineage P.1, that acquired 17 mutations, including a trio in the spike protein (K417T, E484K and N501Y) associated with increased binding to the human ACE2 receptor.
Posted ContentDOI

Report 46: Factors driving extensive spatial and temporal fluctuations in COVID-19 fatality rates in Brazilian hospitals

TL;DR: In this paper, the authors used individual-level patient records following hospitalisation with suspected or confirmed COVID-19 to document the extensive shocks in hospital fatality rates that followed Gamma's spread across 14 state capitals, and in which more than half of hospitalised patients died over sustained time periods.
Journal ArticleDOI

Against All Odds: RNA Extraction From Different Protocols Adapted to Formalin-fixed Paraffin-embedded Tissue.

TL;DR: Evaluating the performance of a method based on phenol-chloroform (PC) and 2 commercial methods for RNA extraction, adapting their protocols for FFPE tissues showed favorable results, demonstrating the viability of the RNA.