M
Myuki A E Crispim
Researcher at Gulf Coast Regional Blood Center
Publications - 20
Citations - 2663
Myuki A E Crispim is an academic researcher from Gulf Coast Regional Blood Center. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 10, co-authored 16 publications receiving 1389 citations.
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Journal ArticleDOI
Genomics and epidemiology of the P.1 SARS-CoV-2 lineage in Manaus, Brazil.
Nuno R. Faria,Thomas A. Mellan,Charles Whittaker,Ingra Morales Claro,Darlan da Silva Candido,Darlan da Silva Candido,Swapnil Mishra,Myuki A E Crispim,Flavia C. S. Sales,Iwona Hawryluk,John T. McCrone,Ruben J.G. Hulswit,Lucas A M Franco,Mariana S. Ramundo,Jaqueline Goes de Jesus,Pamela S Andrade,Thais M. Coletti,Giulia M. Ferreira,Camila A. M. Silva,Erika R. Manuli,Rafael Henrique Moraes Pereira,Pedro S. Peixoto,Moritz U. G. Kraemer,Nelson Gaburo,Cecilia da C. Camilo,Henrique Hoeltgebaum,William Marciel de Souza,Esmenia C. Rocha,Leandro Marques de Souza,Mariana C. Pinho,Leonardo José Tadeu de Araújo,Frederico S V Malta,Aline B. de Lima,Joice do P. Silva,Danielle A G Zauli,Alessandro C. S. Ferreira,Ricardo P Schnekenberg,Daniel J Laydon,Patrick G T Walker,Hannah M. Schlüter,Ana L. P. dos Santos,Maria S. Vidal,Valentina S. Del Caro,Rosinaldo M. F. Filho,Helem M. dos Santos,Renato Santana Aguiar,José Luiz Proença-Módena,Bruce Walker Nelson,James A. Hay,Melodie Monod,Xenia Miscouridou,Helen Coupland,Raphael Sonabend,Michaela A. C. Vollmer,Axel Gandy,Carlos A. Prete,Vitor H. Nascimento,Marc A. Suchard,Thomas A. Bowden,Sergei L Kosakovsky Pond,Chieh-Hsi Wu,Oliver Ratmann,Neil M. Ferguson,Christopher Dye,Nicholas J. Loman,Philippe Lemey,Andrew Rambaut,Nelson Abrahim Fraiji,Maria Perpétuo Socorro Sampaio Carvalho,Oliver G. Pybus,Oliver G. Pybus,Seth Flaxman,Samir Bhatt,Samir Bhatt,Ester Cerdeira Sabino +74 more
TL;DR: In this article, the authors used a two-category dynamical model that integrates genomic and mortality data to estimate that P.1 may be 1.7-to 2.4-fold more transmissible and that previous (non-P.1) infection provides 54 to 79% of the protection against infection with P.
Journal ArticleDOI
Resurgence of COVID-19 in Manaus, Brazil, despite high seroprevalence.
Ester Cerdeira Sabino,Lewis F Buss,Maria Perpétuo Socorro Sampaio Carvalho,Carlos A. Prete,Myuki A E Crispim,Nelson Abrahim Fraiji,Rafael Henrique Moraes Pereira,Kris V Parag,Pedro S. Peixoto,Moritz U. G. Kraemer,Marcio K. Oikawa,Tassila Salomon,Zulma M. Cucunubá,Marcia C. Castro,Andreza Aruska de Souza Santos,Vitor H. Nascimento,Henrique dos Santos Pereira,Neil M. Ferguson,Oliver G. Pybus,Adam J. Kucharski,Michael P. Busch,Christopher Dye,Nuno R. Faria +22 more
Journal ArticleDOI
Three-quarters attack rate of SARS-CoV-2 in the Brazilian Amazon during a largely unmitigated epidemic.
Lewis F Buss,Carlos A. Prete,Claudia M. M. Abrahim,Alfredo Mendrone,Tassila Salomon,Cesar de Almeida-Neto,Rafael F. O. França,Maria C Belotti,Maria Perpétuo Socorro Sampaio Carvalho,Allyson Guimarães Costa,Myuki A E Crispim,Suzete C. Ferreira,Nelson Abrahim Fraiji,Susie Gurzenda,Charles Whittaker,Leonardo Tadashi Kamaura,Pedro L. Takecian,Pedro S. Peixoto,Marcio K. Oikawa,Anna S. Nishiya,Vanderson Rocha,Nanci A. Salles,Andreza Aruska de Souza Santos,Martirene A da Silva,Brian Custer,Kris V Parag,Manoel Barral-Netto,Moritz U. G. Kraemer,Rafael Henrique Moraes Pereira,Oliver G. Pybus,Michael P. Busch,Marcia C. Castro,Christopher Dye,Vitor H. Nascimento,Nuno R. Faria,Nuno R. Faria,Nuno R. Faria,Ester Cerdeira Sabino +37 more
TL;DR: The spread of COVID-19 in Manaus, Brazil, shows that a largely unmitigated epidemic can infect a high fraction of the population and cause high mortality, and confirms that when poorly controlled, CO VID-19 caninfect a large proportion of the Population, causing high mortality.
Journal ArticleDOI
Multiplex qPCR discriminates variants of concern to enhance global surveillance of SARS-CoV-2.
Chantal B.F. Vogels,Mallery I. Breban,Isabel M. Ott,Tara Alpert,Mary E. Petrone,Anne E. Watkins,Chaney C. Kalinich,Rebecca Earnest,Jessica E. Rothman,Jaqueline Goes de Jesus,Ingra Morales Claro,Giulia M. Ferreira,Giulia M. Ferreira,Myuki A E Crispim,Lavanya Singh,Houriiyah Tegally,Ugochukwu J. Anyaneji,Emma B. Hodcroft,Christopher E. Mason,Gaurav Khullar,Jessica Metti,Joel T. Dudley,Matthew MacKay,Megan Nash,Jianhui Wang,Chen Liu,Pei Hui,Steven Murphy,Caleb Neal,Eva Laszlo,Marie L. Landry,Anthony Muyombwe,Randy Downing,Jafar Razeq,Tulio de Oliveira,Nuno R. Faria,Nuno R. Faria,Nuno R. Faria,Ester Cerdeira Sabino,Richard A. Neher,Joseph R. Fauver,Nathan D. Grubaugh +41 more
TL;DR: In this paper, the authors designed and validated an open-source PCR assay to detect SARS-CoV-2 VOC using ORF1a Δ3675-3677 as the primary target and spike Δ69-70 to differentiate.
Posted ContentDOI
Genomics and epidemiology of a novel SARS-CoV-2 lineage in Manaus, Brazil
Nuno R. Faria,Nuno R. Faria,Nuno R. Faria,Thomas A. Mellan,Charles Whittaker,Ingra Morales Claro,Darlan da Silva Candido,Darlan da Silva Candido,Swapnil Mishra,Myuki A E Crispim,Flavia C. S. Sales,Iwona Hawryluk,John T. McCrone,Ruben J.G. Hulswit,Lucas A M Franco,Mariana S. Ramundo,Jaqueline Goes de Jesus,Pamela S Andrade,Thais M. Coletti,Giulia M. Ferreira,Camila A. M. Silva,Erika R. Manuli,Rafael Henrique Moraes Pereira,Pedro S. Peixoto,Moritz U. G. Kraemer,Nelson Gaburo,Cecilia da C. Camilo,Henrique Hoeltgebaum,William Marciel de Souza,Esmenia C. Rocha,Leandro Marques de Souza,Mariana C. Pinho,Leonardo José Tadeu de Araújo,Frederico S V Malta,Aline B. de Lima,Joice do P. Silva,Danielle A G Zauli,Alessandro C. S. Ferreira,Ricardo P Schnekenberg,Daniel J Laydon,Patrick G T Walker,Hannah M. Schlüter,Ana L. P. dos Santos,Maria S. Vidal,Valentina S. Del Caro,Rosinaldo M. F. Filho,Helem M. dos Santos,Renato Santana Aguiar,José Luiz Proença Modena,Bruce Walker Nelson,James A. Hay,Melodie Monod,Xenia Miscouridou,Helen Coupland,Raphael Sonabend,Michaela A. C. Vollmer,Axel Gandy,Marc A. Suchard,Thomas A. Bowden,Sergei L Kosakovsky Pond,Chieh-Hsi Wu,Oliver Ratmann,Neil M. Ferguson,Christopher Dye,Nicholas J. Loman,Philippe Lemey,Andrew Rambaut,Nelson Abrahim Fraiji,Maria Perpétuo Socorro Sampaio Carvalho,Oliver G. Pybus,Oliver G. Pybus,Seth Flaxman,Samir Bhatt,Samir Bhatt,Ester Cerdeira Sabino +74 more
TL;DR: In this paper, the emergence and circulation of a new SARS-CoV-2 variant of concern, lineage P.1, that acquired 17 mutations, including a trio in the spike protein (K417T, E484K and N501Y) associated with increased binding to the human ACE2 receptor.