Ling Huang

TL;DR: The use of a commercially available droplet-based microfluidics platform for high-throughput scRNA-seq to obtain single-cell transcriptomes from protoplasts of more than 10,000 Arabidopsis (Arabidopsis thaliana) root cells demonstrates the feasibility and utility of sc RNA-seq in plants and provides a first-generation gene expression map of the Arabicidopsis root at single- cell resolution.

TL;DR: The TAM system is an essential mediator of microglial recognition and engulfment of amyloid plaques and that TAM-driven micro-glial phagocytosis does not inhibit, but rather promotes, dense-core plaque development.

TL;DR: An ensemble machine learning method is developed that predicts age to a median error of 4 years, outperforming previous methods used to predict age and validated by testing it on ten progeria patients.

TL;DR: It is found that WUSCHEL, a key gene required for apical meristem maintenance, is a cytokinin-dependent B-ARR target gene, demonstrating the importance of the cytokinIn transcription factor network in shoot development.

TL;DR: This work describes this regulatory network and the importance of the multiple feedback loops for its establishment and maintenance in plants and describes the role of transcription factor genes/proteins influencing root epidermis cell fate.