Ling Tian

TL;DR: The data show that larval growth performance is only moderately affected by the nutritionally poor diet, while differences in the activity of digestive enzymes, midgut cell morphology, and accumulation of long-term storage molecules can be observed, indicating that diet-dependent adaptation processes in the midGut ensure the exploitation of poor substrates.

TL;DR: BmE75 isoforms display stage- and tissue-specific responses to 20E at both mRNA and protein levels; moreover, they are regulated by other unknown factors at the protein level.

TL;DR: The evolutionary pattern of the canonical cholesterol biosynthesis pathway (CBP) in the animal kingdom is characterized using both genome-wide analyses and functional experiments and the indispensable utilization processes of cholesterol potentially strengthened the maintenance of the complete set of CBP genes in vertebrates.

TL;DR: It is concluded that 20E regulates larval fat body destruction by upregulating related protease gene expression and protein levels during larval–pupal transition.

TL;DR: It is shown autophagy occurrence in silkworm (Bombyx mori) required BmRpd3, wherein steroid hormone 20-hydroxyecdysone (20E) signaling regulated its protein level and nuclear localization negatively and inhibition of MTORC1 activity led to dephosphorylation and nucleo-cytoplasmic translocation of Bm Rpd3/HsHDAC1.