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Ling Tian

Researcher at South China Agricultural University

Publications -  33
Citations -  7462

Ling Tian is an academic researcher from South China Agricultural University. The author has contributed to research in topics: Bombyx & Autophagy. The author has an hindex of 16, co-authored 30 publications receiving 5891 citations. Previous affiliations of Ling Tian include Chinese Academy of Sciences.

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Journal ArticleDOI

20-Hydroxyecdysone (20E) Primary-response Gene E93 Modulates 20E Signaling to Promote Bombyx Larval-pupal Metamorphosis

TL;DR: E93 transcriptionally modulates 20E signaling to promote Bombyx larval-pupal metamorphosis and acts through the two HTH domains to bind to GAGA-containing motifs present in the Atg1 promoter region for inducing gene expression.
Journal Article

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2459 more
- 01 Jan 2016 - 
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BmATG5 and BmATG6 mediate apoptosis following autophagy induced by 20-hydroxyecdysone or starvation.

TL;DR: Being cleaved into BmATG5-tN and Bm ATG6-C, BmAtG5 and B mATG6 mediate apoptosis following autophagy induced by 20E or starvation in Bombyx Bm-12 cells, reflecting that autophileagy precedes apoptosis in the midgut during BombyX metamorphosis.
Journal ArticleDOI

20-Hydroxyecdysone-induced transcriptional activity of FoxO upregulates brummer and acid lipase-1 and promotes lipolysis in Bombyx fat body

TL;DR: It is concluded that 20E increases the transcriptional activity of FoxO which, in turn, upregulates brummer and acid lipase-1 and induces lipolysis in the Bombyx fat body during molting and pupation.
Journal ArticleDOI

Transcriptional regulation of the insulin signaling pathway genes by starvation and 20-hydroxyecdysone in the Bombyx fat body.

TL;DR: It is concluded that 20E slowly reduces food consumption and then indirectly induces a state of starvation resulting in the elevation of the mRNA levels of InR, IRS, PI3K110, and PDK in the Bombyx fat body during molting and pupation.