L
Lisa Budzinski
Publications - 4
Citations - 129
Lisa Budzinski is an academic researcher. The author has contributed to research in topics: Antigen & Acquired immune system. The author has an hindex of 2, co-authored 3 publications receiving 37 citations.
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Journal ArticleDOI
SARS-CoV-2 in severe COVID-19 induces a TGF-β-dominated chronic immune response that does not target itself.
Marta Ferreira-Gomes,Andrey Kruglov,Andrey Kruglov,Pawel Durek,Frederik Heinrich,Caroline Tizian,Gitta Anne Heinz,Anna Pascual-Reguant,Weijie Du,Ronja Mothes,Chaofan Fan,Stefan Frischbutter,Katharina Habenicht,Lisa Budzinski,Justus Ninnemann,Péter K. Jani,Gabriela Maria Guerra,Katrin Lehmann,Mareen Matz,Lennard Ostendorf,Lukas Heiberger,Hyun-Dong Chang,Sandy Bauherr,Marcus Maurer,Günther Schönrich,Martin Raftery,Tilmann Kallinich,Marcus A. Mall,Stefan Angermair,Sascha Treskatsch,Thomas Dörner,Victor M. Corman,Andreas Diefenbach,Hans-Dieter Volk,Hans-Dieter Volk,Sefer Elezkurtaj,Thomas Winkler,Jun Dong,Anja E. Hauser,Helena Radbruch,Mario Witkowski,Fritz Melchers,Andreas Radbruch,Mir-Farzin Mashreghi +43 more
TL;DR: In this article, a single cell level analysis of plasmablasts egressed into the blood to study the dynamics of adaptive immune response in COVID-19 patients requiring intensive care.
Posted ContentDOI
In severe COVID-19, SARS-CoV-2 induces a chronic, TGF-β-dominated adaptive immune response
Marta Ferreira-Gomes,Andrey Kruglov,Pawel Durek,Frederik Heinrich,Caroline Tizian,Anne Heinz G,Pascual-Reguant A,Du W,Ronja Mothes,Fan C,Stefan Frischbutter,Katharina Habenicht,Lisa Budzinski,Justus Ninnemann,Péter K. Jani,Gabriela Maria Guerra,Katrin Lehmann,Mareen Matz,Lennard Ostendorf,Lukas Heiberger,H.-D. Chang,Sandy Bauherr,Marcus Maurer,Günther Schönrich,Martin Raftery,Tilmann Kallinich,Alexander Mall M,Stefan Angermair,Sascha Treskatsch,Thomas Dörner,Max Corman,Andreas Diefenbach,Hans-Dieter Volk,Sefer Elezkurtaj,Thomas Winkler,Dong J,Erika Hauser A,Helena Radbruch,Mario Witkowski,Fritz Melchers,Andreas Radbruch,Mir-Farzin Mashreghi +41 more
TL;DR: In severely affected COVID-19 patients SARS-CoV-2 triggers chronic immune reactions which are controlled by TGF-{beta}, with most of the activated B cells being no longer specific for the Sars-Cov-2 spike protein and its receptor binding domain, nor for nucleoprotein.
Posted ContentDOI
Induction of cross-reactive antibody responses against the RBD domain of the spike protein of SARS-CoV-2 by commensal microbiota
Justus Ninnemann,Lisa Budzinski,Marina Bondareva,Mario Witkowski,Stefan Angermair,Jakob Kreye,Pawel Durek,Momsen Reincke,Momsen Reincke,Elisa Sanchez-Sendin,Elisa Sanchez-Sendin,Elisa Sanchez-Sendin,Selin Yilmaz,Toni Sempert,Gitta Anne Heinz,Caroline Tizian,Martin Raftery,Guenther Schoenrich,Daria Matyushkina,Ivan V. Smirnov,Vadim M. Govorun,Eva Schrezenmeier,Thomas Doerner,Silvia Zocche,Edoardo Viviano,Katharina Johanna Sehmsdorf,Hyun-Dong Chang,Philipp Enghard,Sascha Treskatsch,Andreas Radbruch,Andreas Diefenbach,Harald Pruess,Harald Pruess,Harald Pruess,Mir-Farzin Mashreghi,Andrey Kruglov,Andrey Kruglov +36 more
TL;DR: In this paper, the authors reported that several commensal bacteria contribute to the generation of cross-reactive IgA antibodies against the receptor-binding domain (RBD) of the SARS-CoV-2 Spike protein.
Journal ArticleDOI
Rapid detection and online analysis of microbial changes through flow cytometry
J Kupschus,Stefan Janssen,Andreas Hoek,Jaques Kuska,Jonathan Rathjens,C. Sonntag,Katja Ickstadt,Lisa Budzinski,Hyun-Dong Chang,Andrea Rossi,Charlotte Esser,Katrin Hochrath +11 more
TL;DR: The FlowSoFine tool as mentioned in this paper enables the generation and comparison of cytometric fingerprints of microbial communities from different sources using flow cytometry and 16'S rRNA gene amplicon sequencing.