M
Mareen Matz
Researcher at Charité
Publications - 27
Citations - 1139
Mareen Matz is an academic researcher from Charité. The author has contributed to research in topics: Transplantation & Kidney transplantation. The author has an hindex of 15, co-authored 25 publications receiving 966 citations.
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Journal ArticleDOI
The microRNA miR-182 is induced by IL-2 and promotes clonal expansion of activated helper T lymphocytes
Anna-Barbara Stittrich,Claudia Haftmann,Evridiki Sgouroudis,Anja A. Kühl,Ahmed N. Hegazy,Isabel Panse,René Riedel,Michael Flossdorf,Jun Dong,Franziska Fuhrmann,Gitta Anne Heinz,Zhuo Fang,Na Li,Ute Bissels,Farahnaz Hatam,Angelina Jahn,Ben Hammoud,Mareen Matz,Felix Michael Schulze,Ria Baumgrass,Andreas Bosio,Hans-Joachim Mollenkopf,Joachim R. Grün,Andreas Thiel,Wei Chen,Thomas Höfer,Christoph Loddenkemper,Max Löhning,Hyun-Dong Chang,Nikolaus Rajewsky,Andreas Radbruch,Mir-Farzin Mashreghi +31 more
TL;DR: A central role for miR-182 is demonstrated in the physiological regulation of IL-2-driven helper T cell–mediated immune responses and new therapeutic possibilities are opened.
Journal ArticleDOI
Early post-transplant urinary IP-10 expression after kidney transplantation is predictive of short- and long-term graft function
Mareen Matz,J Beyer,D Wunsch,Mir-Farzin Mashreghi,Marleen Seiler,Johann Pratschke,Nina Babel,Hans-Dieter Volk,Petra Reinke,Katja Kotsch +9 more
TL;DR: Evaluated urine data reveal a correlation between elevated IP-10 expression in urine at early time points post-transplantation and intragraft immune activation that leads to acute rejection and compromised long-term graft function.
Journal ArticleDOI
SARS-CoV-2 in severe COVID-19 induces a TGF-β-dominated chronic immune response that does not target itself.
Marta Ferreira-Gomes,Andrey Kruglov,Andrey Kruglov,Pawel Durek,Frederik Heinrich,Caroline Tizian,Gitta Anne Heinz,Anna Pascual-Reguant,Weijie Du,Ronja Mothes,Chaofan Fan,Stefan Frischbutter,Katharina Habenicht,Lisa Budzinski,Justus Ninnemann,Péter K. Jani,Gabriela Maria Guerra,Katrin Lehmann,Mareen Matz,Lennard Ostendorf,Lukas Heiberger,Hyun-Dong Chang,Sandy Bauherr,Marcus Maurer,Günther Schönrich,Martin Raftery,Tilmann Kallinich,Marcus A. Mall,Stefan Angermair,Sascha Treskatsch,Thomas Dörner,Victor M. Corman,Andreas Diefenbach,Hans-Dieter Volk,Hans-Dieter Volk,Sefer Elezkurtaj,Thomas Winkler,Jun Dong,Anja E. Hauser,Helena Radbruch,Mario Witkowski,Fritz Melchers,Andreas Radbruch,Mir-Farzin Mashreghi +43 more
TL;DR: In this article, a single cell level analysis of plasmablasts egressed into the blood to study the dynamics of adaptive immune response in COVID-19 patients requiring intensive care.
Journal ArticleDOI
Enhanced granulysin mRNA expression in urinary sediment in early and delayed acute renal allograft rejection.
Katja Kotsch,Mir-Farzin Mashreghi,Gantuja Bold,Philipp Tretow,Jana Beyer,Mareen Matz,J. Hoerstrup,Johann Pratschke,Ruchuang Ding,Manikkam Suthanthiran,Hans-Dieter Volk,Petra Reinke +11 more
TL;DR: The authors’ data illustrate that the noninvasive kinetic mRNA expression measurement of defined markers in urinary cells of renal allograft recipients allows the early nonin invasive detection of ongoing aRx.
Journal ArticleDOI
Heightened expression of the cytotoxicity receptor NKG2D correlates with acute and chronic nephropathy after kidney transplantation.
Marleen Seiler,Irena Brabcova,Ondrej Viklicky,Petra Hribova,Christian Rosenberger,Johann Pratschke,A. Lodererova,Mareen Matz,Constanze Schönemann,Petra Reinke,Hans-Dieter Volk,Katja Kotsch +11 more
TL;DR: Elevated levels of NKG2D mRNA expression were associated with restricted long‐term graft function assessed by the glomerular filtration rate at 6, 12 and 18 months posttransplantation, suggesting this receptor as a new candidate marker for the diagnosis of acute and chronic allograft rejection.