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Thomas Winkler

Researcher at University of Erlangen-Nuremberg

Publications -  218
Citations -  12661

Thomas Winkler is an academic researcher from University of Erlangen-Nuremberg. The author has contributed to research in topics: Antibody & B cell. The author has an hindex of 53, co-authored 201 publications receiving 10662 citations. Previous affiliations of Thomas Winkler include Hoffmann-La Roche & Harvard University.

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Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition)

Andrea Cossarizza, +462 more
- 01 Oct 2019 - 
TL;DR: These guidelines are a consensus work of a considerable number of members of the immunology and flow cytometry community providing the theory and key practical aspects offlow cytometry enabling immunologists to avoid the common errors that often undermine immunological data.
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The EMT-activator Zeb1 is a key factor for cell plasticity and promotes metastasis in pancreatic cancer

Angela M. Krebs, +19 more
- 01 May 2017 - 
TL;DR: It is shown that different EMT-TFs have complementary subfunctions in driving pancreatic tumour metastasis, and that Depletion of Zeb1 suppresses stemness, colonization capacity and in particular phenotypic/metabolic plasticity of tumour cells, probably causing the observed in vivo effects.
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The proteasome inhibitor bortezomib depletes plasma cells and protects mice with lupus-like disease from nephritis.

Kirsten Neubert, +10 more
- 01 Jul 2008 - 
TL;DR: It is shown that the proteasome inhibitor bortezomib, which is approved for the treatment of multiple myeloma, eliminates both short- and long-lived plasma cells by activation of the terminal unfolded protein response.
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Down-regulation of RAG1 and RAG2 gene expression in preB cells after functional immunoglobulin heavy chain rearrangement.

Ulf Grawunder, +6 more
- 01 Nov 1995 - 
TL;DR: It is shown that the expression of the RAG genes is twice up- and down-regulated, at the transcriptionallevel for RAG1 and RAG2, and at the postranscriptional level for R AG2 protein.
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Eltrombopag Added to Standard Immunosuppression for Aplastic Anemia.

Danielle M. Townsley, +17 more
- 19 Apr 2017 - 
TL;DR: The addition of eltrombopag to immunosuppressive therapy was associated with markedly higher rates of hematologic response among patients with severe aplastic anemia than in a historical cohort.