Hyun-Dong Chang

TL;DR: In this article, a single cell level analysis of plasmablasts egressed into the blood to study the dynamics of adaptive immune response in COVID-19 patients requiring intensive care.

TL;DR: In this paper, the authors discuss a paradigm shift by suggesting that chronic inflammation is driven by imprinted, pathogenic "memory" cells of the immune system, which can also involve cells of innate immunity.

TL;DR: In this article, the role of T-bet in regulating fetal ILC3 and lymphoid tissue inducer (LTi) activity and expressing the master transcription factor RORγt was identified.

TL;DR: Bone marrow has emerged as a preferred resting place for memory lymphocytes providing both local and systemic long-term protection as discussed by the authors, where mesenchymal stromal cells provide a privileged environment for quiescent memory B and T lymphocytes, the protagonists of secondary immune reactions.

TL;DR: In this article, an integrin-mediated contact to the stromal cell provides an essential survival signal to the plasma cell, activating the PI3K signalling pathway, downregulating FoxO1/3a and repressing the activation of caspases 3 and 7.