L
Lisa Garrett
Researcher at National Institutes of Health
Publications - 59
Citations - 6516
Lisa Garrett is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Gene & Transgene. The author has an hindex of 27, co-authored 57 publications receiving 6117 citations. Previous affiliations of Lisa Garrett include Salk Institute for Biological Studies.
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Journal ArticleDOI
Stat5a is mandatory for adult mammary gland development and lactogenesis.
Xiuwen Liu,Gertraud W. Robinson,Kay Uwe Wagner,Lisa Garrett,Anthony Wynshaw-Boris,Lothar Hennighausen +5 more
TL;DR: It is document that Stat5a is the principal and an obligate mediator of mammopoietic and lactogenic signaling.
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Cre-mediated gene deletion in the mammary gland.
Kay Uwe Wagner,Robert J. Wall,Luc St-Onge,Peter Gruss,Anthony Wynshaw-Boris,Lisa Garrett,Minglin Li,Priscilla A. Furth,Lothar Hennighausen +8 more
TL;DR: The results show that transgenic mice with WAP-Cre but not MMTV-Cre can be used as a powerful tool to study gene function in development and tumorigenesis in the mammary gland.
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Mammalian Mst1 and Mst2 kinases play essential roles in organ size control and tumor suppression
Hai Song,Kinglun Kingston Mak,Lilia Topol,Kangsun Yun,Jianxin Hu,Lisa Garrett,Yongbin Chen,Ogyi Park,Jia Chang,R. Mark Simpson,Cun-Yu Wang,Bin Gao,Jin Jiang,Yingzi Yang +13 more
TL;DR: It is found that Mst1 and Mst2, the two mouse homologs of the Drosophila Hpo, control the sizes of some, but not all organs, in mice, and MSt1 andMst2 act as tumor suppressors by restricting cell proliferation and survival.
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Wnt Signaling Gradients Establish Planar Cell Polarity by Inducing Vangl2 Phosphorylation through Ror2
Bo Gao,Hai Song,Kevin Bishop,Gene Elliot,Lisa Garrett,Milton A. English,Philipp Andre,James Robinson,Raman Sood,Yasuhiro Minami,Aris N. Economides,Yingzi Yang +11 more
TL;DR: Wnt signaling gradient provides directional information to a field of cells and provides new insight to Robinow syndrome, Brachydactyly Type B1, and spinal bifida which are caused by mutations in human ROR2, WNT5A, or VANGL.
Journal ArticleDOI
Behavioural abnormalities and selective neuronal loss in HD transgenic mice expressing mutated full-length HD cDNA
P. Hemachandra Reddy,Maya Williams,Vinod Charles,Lisa Garrett,Lisa Pike-Buchanan,William O. Whetsell,Georgina F. Miller,Danilo A. Tagle +7 more
TL;DR: Transgenic mice represent clinically relevant models for HD pathogenesis, and may provide insights into the underlying pathophysiological mechanisms of other triplet repeat disorders.