L
Lixin Duan
Researcher at Chinese Ministry of Education
Publications - 30
Citations - 1003
Lixin Duan is an academic researcher from Chinese Ministry of Education. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 10, co-authored 19 publications receiving 723 citations. Previous affiliations of Lixin Duan include Guangzhou University of Chinese Medicine & University of Arizona.
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Journal ArticleDOI
Biosynthesis, regulation, and domestication of bitterness in cucumber
Yi Shang,Yongshuo Ma,Yuan Zhou,Huimin Zhang,Lixin Duan,Huiming Chen,Jianguo Zeng,Qian Zhou,Shenhao Wang,Wenjia Gu,Min Liu,Jinwei Ren,Xingfang Gu,Shengping Zhang,Wang Ye,Ken Yasukawa,Harro J. Bouwmeester,Xiaoquan Qi,Zhonghua Zhang,William J. Lucas,Sanwen Huang +20 more
TL;DR: Along the way, Shang et al. have worked out the biosynthetic pathway of cucurbitacin and discovered genetic traces of the domestication process and unraveled the mystery of why some cucumbers, if grown in chilly conditions, become bitter.
Journal ArticleDOI
Convergence and divergence of bitterness biosynthesis and regulation in Cucurbitaceae.
Yuan Zhou,Yongshuo Ma,Jianguo Zeng,Lixin Duan,Xiaofeng Xue,Huaisong Wang,Tao Lin,Zhiqiang Liu,Ke-Wu Zeng,Yang Zhong,Shu Zhang,Qun Hu,Min Liu,Huimin Zhang,James Reed,Tessa Moses,Xinyan Liu,Peng Huang,Zhixing Qing,Xiubin Liu,Peng-Fei Tu,Hanhui Kuang,Zhonghua Zhang,Anne Osbourn,Dae-Kyun Ro,Yi Shang,Sanwen Huang +26 more
TL;DR: Comparison of the genomes of cucumber, melon and watermelon uncovered conserved syntenic loci encoding metabolic genes for distinct cucurbitacins and discovered a syntenic gene cluster of transcription factors that regulates the tissue-specific biosynthesis of cucurbits and may confer the loss of bitterness phenotypes associated with convergent domestication of wild cucurbits.
Journal ArticleDOI
Divergent evolution of oxidosqualene cyclases in plants
Zheyong Xue,Lixin Duan,Dan Liu,Jie Guo,Song Ge,Jo Dicks,Paul E. O'Maille,Anne Osbourn,Xiaoquan Qi +8 more
TL;DR: The phylogenetic analysis suggests that expansion of OSC members in higher plants has occurred mainly through tandem duplication followed by positive selection and diversifying evolution, and consolidated the previous suggestion that dicot triterpene synthases have been derived from an ancestral lanosterol synthase instead of directly from their cycloartenol synthases.
Journal ArticleDOI
Functional Divergence of Diterpene Syntheses in the Medicinal Plant Salvia miltiorrhiza
Guanghong Cui,Lixin Duan,Baolong Jin,Jun Qian,Zheyong Xue,Guoan Shen,John Hugh Snyder,Jingyuan Song,Shilin Chen,Luqi Huang,Reuben J. Peters,Xiaoquan Qi +11 more
TL;DR: Molecular insights are provided into the evolutionary diversification of functional diterpenoids in plants and the correlation between conservation pattern and stereochemical product outcome of the CPSs observed here suggests a degree of correlation that, especially when combined with the identity of certain key residues, may be predictive.
Journal ArticleDOI
Use of the Metabolomics Approach to Characterize Chinese Medicinal Material Huangqi
Lixin Duan,Tianlu Chen,Ming‐ming Li,Min-Min Chen,Ye-Qing Zhou,Guang-Hong Cui,Aihua Zhao,Wei Jia,Huang Luqi,Xiaoquan Qi +9 more
TL;DR: AFLP based genetic fingerprinting and GC-TOF/MS-based metabolic fingerprinting were used to successfully discriminate the two species and the results of AFLP supported the opinion that Menggu Huangqi was a variant of Mojia Huangqi.