Lucie Rodriguez

TL;DR: The inflammatory response in MIS-C differs from the cytokine storm of severe acute COVID-19, shares several features with Kawasaki disease, but also differs from this condition with respect to T cell subsets, interleukin (IL)-17A, and biomarkers associated with arterial damage.

TL;DR: The inflammatory response in MIS-C differs from the cytokine storm of severe acute COVID-19, is more similar to Kawasaki disease, but also differ from this with respect to T-cell subsets, IL-17A and biomarkers associated with arterial damage.

TL;DR: This article showed that a lack of bifidobacteria, and in particular depletion of genes required for human milk oligosaccharide utilization from the metagenome, is associated with systemic inflammation and immune dysregulation early in life.

TL;DR: An ordered sequence of immune changes after birth, driven by microbial interactions is mapped, triggered by microbial colonization that distinguish children with different gut bacterial composition.

TL;DR: An IFNγ – Eosinophil axis activated prior to lung hyperinflammation and changes in cell-cell coregulation during different stages of the disease are described and map an immune trajectory during recovery that is shared among patients with severe COVID-19.