Lev Levanov

TL;DR: It is found that neuropilin-1 (NRP1), known to bind furin-cleaved substrates, significantly potentiates SARS-CoV-2 infectivity, an effect blocked by a monoclonal blocking antibody against NRP1.

TL;DR: A case of a pregnant woman and her fetus infected with ZIKV during the 11th gestational week and postmortem analysis of the fetal brain finds substantial brain abnormalities without the presence of microcephaly or intracranial calcifications is described.

TL;DR: Findings provide additional evidence for the association between congenital ZIKV infection and fetal brain damage and future studies focusing on infection at various gestational ages may provide better insight into the role of ZikV infection in abnormal brain development and further tools for detection.

TL;DR: An IFNγ – Eosinophil axis activated prior to lung hyperinflammation and changes in cell-cell coregulation during different stages of the disease are described and map an immune trajectory during recovery that is shared among patients with severe COVID-19.

TL;DR: It is found that the cellular receptor neuropilin-1 (NRP1), known to bind furin-cleaved substrates, significantly potentiates SARS-CoV-2 infectivity, which was inhibited by a monoclonal blocking antibody against the extracellular b1b2 domain of NRP1.