L
Lucie Y Li
Researcher at Harvard University
Publications - 8
Citations - 330
Lucie Y Li is an academic researcher from Harvard University. The author has contributed to research in topics: Epitope & Monoclonal antibody. The author has an hindex of 3, co-authored 4 publications receiving 184 citations. Previous affiliations of Lucie Y Li include Humboldt University of Berlin.
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Journal ArticleDOI
A Therapeutic Non-self-reactive SARS-CoV-2 Antibody Protects from Lung Pathology in a COVID-19 Hamster Model.
Jakob Kreye,S. Momsen Reincke,Hans Christian Kornau,Hans Christian Kornau,Elisa Sanchez-Sendin,Elisa Sanchez-Sendin,Elisa Sanchez-Sendin,Victor M. Corman,Hejun Liu,Meng Yuan,Nicholas C. Wu,Xueyong Zhu,Chang-Chun D Lee,Jakob Trimpert,Markus Höltje,Kristina Dietert,Laura Stöffler,Laura Stöffler,Niels von Wardenburg,Niels von Wardenburg,Scott van Hoof,Scott van Hoof,Scott van Hoof,Marie A Homeyer,Marie A Homeyer,Julius Hoffmann,Julius Hoffmann,Azza Abdelgawad,Achim D. Gruber,Luca D. Bertzbach,Daria Vladimirova,Lucie Y Li,Lucie Y Li,Paula Charlotte Barthel,Karl Skriner,Andreas C. Hocke,Stefan Hippenstiel,Martin Witzenrath,Norbert Suttorp,Florian Kurth,Florian Kurth,Christiana Franke,Matthias Endres,Dietmar Schmitz,Dietmar Schmitz,Lara Maria Jeworowski,Anja Richter,Marie Luisa Schmidt,Tatjana Schwarz,Marcel A. Müller,Christian Drosten,Daniel Wendisch,Leif E. Sander,Nikolaus Osterrieder,Nikolaus Osterrieder,Ian A. Wilson,Harald Prüss,Harald Prüss,Harald Prüss +58 more
TL;DR: Results show that non-self-reactive virus-neutralizing mAbs elicited during SARS-CoV-2 infection are a promising therapeutic strategy and should be guided by immunization strategies.
Posted ContentDOI
A SARS-CoV-2 neutralizing antibody protects from lung pathology in a COVID-19 hamster model
Jakob Kreye,S. Momsen Reincke,Hans-Christian Kornau,Hans-Christian Kornau,Elisa Sanchez-Sendin,Elisa Sanchez-Sendin,Elisa Sanchez-Sendin,Victor M. Corman,Hejun Liu,Meng Yuan,Nicholas C. Wu,Xueyong Zhu,Chang-Chun D Lee,Jakob Trimpert,Markus Höltje,Kristina Dietert,Laura Stöffler,Laura Stöffler,Niels von Wardenburg,Niels von Wardenburg,Scott van Hoof,Scott van Hoof,Scott van Hoof,Marie A Homeyer,Marie A Homeyer,Julius Hoffmann,Julius Hoffmann,Azza Abdelgawad,Achim D. Gruber,Luca D. Bertzbach,Daria Vladimirova,Lucie Y Li,Lucie Y Li,Paula Charlotte Barthel,Karl Skriner,Andreas C. Hocke,Stefan Hippenstiel,Martin Witzenrath,Norbert Suttorp,Florian Kurth,Florian Kurth,Christiana Franke,Matthias Endres,Dietmar Schmitz,Dietmar Schmitz,Lara Maria Jeworowski,Anja Richter,Marie Luisa Schmidt,Tatjana Schwarz,Marcel A. Müller,Christian Drosten,Daniel Wendisch,Leif E. Sander,Nikolaus Osterrieder,Ian A. Wilson,Harald Prüss,Harald Prüss,Harald Prüss +57 more
TL;DR: Results show that non-self-reactive virus-neutralizing mAbs elicited during SARS-CoV-2 infection are a promising therapeutic strategy and should be guided by immunization strategies.
Posted ContentDOI
Evidence for a role of calcium in STING signaling
TL;DR: It is proposed that intracellular calcium plays an important role in the response of the STING pathway, and in response to DMXAA, calcium is mobilized form the ER and required for signaling, while in the case of cGAMP calcium is mobilize but not required.
Journal ArticleDOI
A Sars-Cov-2 Neutralizing Antibody Protects from Lung Pathology in a Covid-19 Hamster Model
Jakob Kreye,S. Momsen Reincke,Hans-Christian Kornau,Elisa Sanchez-Sendin,Victor M. Corman,Hejun Liu,Meng Yuan,Nicholas C. Wu,Xueyong Zhu,Chang-Chun D Lee,Jakob Trimpert,Markus Hoeltje,Kristina Dietert,Laura Stoeffler,Niels von Wardenburg,Scott van Hoof,Marie A Homeyer,Julius Hoffmann,Azza Abdelgawad,Achim D. Gruber,Luca D. Bertzbach,Daria Vladimirova,Lucie Y Li,Paula Charlotte Barthel,Karl Skriner,Andreas C. Hocke,Stefan Hippenstiel,Martin Witzenrath,Norbert Suttorp,Florian Kurth,Christiana Franke,Matthias Endres,Dietmar Schmitz,Lara Maria Jeworowski,Anja Richter,Marie Luisa Schmidt,Tatjana Schwarz,Marcel A Mueller,Christian Drosten,Daniel Wendisch,Leif E. Sander,Nikolaus Osterrieder,Ian A. Wilson,Harald Pruess +43 more
TL;DR: Among 598 human monoclonal antibodies (mAbs) from ten SARS-CoV-2 patients, this article identified 40 strongly neutralizing mAbs, including CV07-209, which achieved IC 50 of 3.1 ng/ml.
Journal ArticleDOI
Beta variant COVID-19 protein booster vaccine elicits durable cross-neutralization against SARS-CoV-2 variants in non-human primates
Vincent Pavot,Catherine C. Berry,Michael G. Kishko,Natalie Anosova,Lucie Y Li,Timothy Tibbitts,Dean Huang,Alice Raillard,Sylviane Gautheron,Cindy Gutzeit,Marguerite Koutsoukos,Roman M. Chicz,Valerie Lecouturier +12 more
TL;DR: This paper showed that the monovalent Beta vaccine with AS03 adjuvant induces durable cross-neutralizing antibody responses against the prototype strain D614G as well as variants Delta (B.617.2), Omicron (BA.1 and BA.4/5) and SARS-CoV-1, that are still detectable in all macaques 6 months post-booster.