Markus Höltje

TL;DR: It is shown that mice selectively deficient in peripheral TPH and serotonin exhibit impaired hemostasis, resulting in a reduced risk of thrombosis and thromboembolism, although the ultrastructure of the platelets is not affected.

TL;DR: To determine the presence and kinetics of antibodies against synaptic proteins in patients with herpes simplex virus encephalitis, a large number of patients with HSE are treated with antiretroviral medication.

TL;DR: Six of 7 cases with the indicated clinical criteria had anti-NMDAR encephalitis, which represented 1% of all young patients' admissions to the ICU, and NMDAR antibodies should be tested in all patients withEncephalitis who fulfill these criteria.

TL;DR: Results show that non-self-reactive virus-neutralizing mAbs elicited during SARS-CoV-2 infection are a promising therapeutic strategy and should be guided by immunization strategies.

TL;DR: A subset of patients with slowly progressive cognitive impairment has an underlying synaptic autoimmunity that decreases the density of NMDAR and other synaptic proteins, and alters synaptic currents, and can be demonstrated examining patients' serum and CSF for N MDAR IgA antibodies, identifying possible candidates for immunotherapy.