L
Lara Maria Jeworowski
Researcher at Humboldt University of Berlin
Publications - 17
Citations - 466
Lara Maria Jeworowski is an academic researcher from Humboldt University of Berlin. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 5, co-authored 8 publications receiving 214 citations. Previous affiliations of Lara Maria Jeworowski include German Cancer Research Center & University of Bonn.
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Journal ArticleDOI
A Therapeutic Non-self-reactive SARS-CoV-2 Antibody Protects from Lung Pathology in a COVID-19 Hamster Model.
Jakob Kreye,S. Momsen Reincke,Hans Christian Kornau,Hans Christian Kornau,Elisa Sanchez-Sendin,Elisa Sanchez-Sendin,Elisa Sanchez-Sendin,Victor M. Corman,Hejun Liu,Meng Yuan,Nicholas C. Wu,Xueyong Zhu,Chang-Chun D Lee,Jakob Trimpert,Markus Höltje,Kristina Dietert,Laura Stöffler,Laura Stöffler,Niels von Wardenburg,Niels von Wardenburg,Scott van Hoof,Scott van Hoof,Scott van Hoof,Marie A Homeyer,Marie A Homeyer,Julius Hoffmann,Julius Hoffmann,Azza Abdelgawad,Achim D. Gruber,Luca D. Bertzbach,Daria Vladimirova,Lucie Y Li,Lucie Y Li,Paula Charlotte Barthel,Karl Skriner,Andreas C. Hocke,Stefan Hippenstiel,Martin Witzenrath,Norbert Suttorp,Florian Kurth,Florian Kurth,Christiana Franke,Matthias Endres,Dietmar Schmitz,Dietmar Schmitz,Lara Maria Jeworowski,Anja Richter,Marie Luisa Schmidt,Tatjana Schwarz,Marcel A. Müller,Christian Drosten,Daniel Wendisch,Leif E. Sander,Nikolaus Osterrieder,Nikolaus Osterrieder,Ian A. Wilson,Harald Prüss,Harald Prüss,Harald Prüss +58 more
TL;DR: Results show that non-self-reactive virus-neutralizing mAbs elicited during SARS-CoV-2 infection are a promising therapeutic strategy and should be guided by immunization strategies.
Posted ContentDOI
Mapping SARS-CoV-2 antigenic relationships and serological responses
S. H. Wilks,Barbara Mühlemann,Xiaoying Shen,Sina Türeli,Eric B. LeGresley,Antonia Netzl,Miguela A. Caniza,Jesus N Chacaltana-Huarcaya,Victor M. Corman,Xiaoju Daniell,Michael B. Datto,Fatimah S. Dawood,Thomas N. Denny,Christian Drosten,Ron A. M. Fouchier,Patricia García,Peter Halfmann,Agatha N. Jassem,Lara Maria Jeworowski,Terry Jones,Yoshihiro Kawaoka,Florian Krammer,Charlene McDanal,Rolando Pajon,Viviana Simon,Melissa S. Stockwell,Haili Tang,Harm van Bakel,Vic Veguilla,Richard J. Webby,David C. Montefiori,Derek J. Smith +31 more
TL;DR: Antigenic cartography of SARS-CoV-2 variants reveals amino acid substitutions governing immune escape and immunodominance patterns, with implications for variant risk assessment and vaccine strain selection.
Posted ContentDOI
A SARS-CoV-2 neutralizing antibody protects from lung pathology in a COVID-19 hamster model
Jakob Kreye,S. Momsen Reincke,Hans-Christian Kornau,Hans-Christian Kornau,Elisa Sanchez-Sendin,Elisa Sanchez-Sendin,Elisa Sanchez-Sendin,Victor M. Corman,Hejun Liu,Meng Yuan,Nicholas C. Wu,Xueyong Zhu,Chang-Chun D Lee,Jakob Trimpert,Markus Höltje,Kristina Dietert,Laura Stöffler,Laura Stöffler,Niels von Wardenburg,Niels von Wardenburg,Scott van Hoof,Scott van Hoof,Scott van Hoof,Marie A Homeyer,Marie A Homeyer,Julius Hoffmann,Julius Hoffmann,Azza Abdelgawad,Achim D. Gruber,Luca D. Bertzbach,Daria Vladimirova,Lucie Y Li,Lucie Y Li,Paula Charlotte Barthel,Karl Skriner,Andreas C. Hocke,Stefan Hippenstiel,Martin Witzenrath,Norbert Suttorp,Florian Kurth,Florian Kurth,Christiana Franke,Matthias Endres,Dietmar Schmitz,Dietmar Schmitz,Lara Maria Jeworowski,Anja Richter,Marie Luisa Schmidt,Tatjana Schwarz,Marcel A. Müller,Christian Drosten,Daniel Wendisch,Leif E. Sander,Nikolaus Osterrieder,Ian A. Wilson,Harald Prüss,Harald Prüss,Harald Prüss +57 more
TL;DR: Results show that non-self-reactive virus-neutralizing mAbs elicited during SARS-CoV-2 infection are a promising therapeutic strategy and should be guided by immunization strategies.
Journal ArticleDOI
Immunological Effects and Viral Gene Expression Determine the Efficacy of Oncolytic Measles Vaccines Encoding IL-12 or IL-15 Agonists
Paul S. Backhaus,Rūta Veinalde,Laura Hartmann,Laura Hartmann,Jessica E. Dunder,Jessica E. Dunder,Lara Maria Jeworowski,Jessica Albert,Jessica Albert,Birgit Hoyler,Birgit Hoyler,Tanja Poth,Dirk Jäger,Dirk Jäger,Guy Ungerechts,Christine E. Engeland,Christine E. Engeland +16 more
TL;DR: MeVac encoding a human IL-12 fusion protein was developed for future clinical translation after results showed that MeVac FmIL-12 showed more robust viral gene expression and immune activation, resulting in superior anti-tumor efficacy.
Journal ArticleDOI
Pausing methotrexate improves immunogenicity of COVID-19 vaccination in elderly patients with rheumatic diseases
Amanthi Nadira Arumahandi de Silva,Leonie Maria Frommert,Fredrik N. Albach,Jens Klotsche,V. Scholz,Lara Maria Jeworowski,Tatjana Schwarz,A. ten Hagen,Jan Zernicke,Victor M. Corman,Christian Drosten,Gerd R Burmester,Robert Biesen +12 more
TL;DR: MTX reduces the immunogenicity of SARS-CoV-2 vaccination in an age-dependent manner and suggests that holding MTX for at least 10 days after vaccination significantly improves the antibody response in patients over 60 years of age.