L
Luicer A. Ingasia
Researcher at Kenya Medical Research Institute
Publications - 12
Citations - 151
Luicer A. Ingasia is an academic researcher from Kenya Medical Research Institute. The author has contributed to research in topics: Plasmodium falciparum & Malaria. The author has an hindex of 6, co-authored 10 publications receiving 120 citations. Previous affiliations of Luicer A. Ingasia include United States Army Medical Research Unit-Kenya.
Papers
More filters
Journal ArticleDOI
Temporal trends in prevalence of Plasmodium falciparum molecular markers selected for by artemether–lumefantrine treatment in pre-ACT and post-ACT parasites in western Kenya
Angela O. Achieng,Peninah Muiruri,Luicer A. Ingasia,Benjamin Opot,Dennis W. Juma,Redemptah Yeda,Bidii S. Ngalah,Bernhards Ogutu,Ben Andagalu,Hoseah M. Akala,Edwin Kamau +10 more
TL;DR: There is a significant change in parasite genotype, with key molecular determinants of AL selection almost reaching saturation, and there is need to closely monitor parasite genotypic, phenotypic and clinical dynamics in response to continued use of AL in western Kenya.
Journal ArticleDOI
Polymorphisms in Pfmdr1, Pfcrt, and Pfnhe1 Genes Are Associated with Reduced In Vitro Activities of Quinine in Plasmodium falciparum Isolates from Western Kenya
Jelagat Cheruiyot,Luicer A. Ingasia,Angela A. Omondi,Angela A. Omondi,Dennis W. Juma,Benjamin Opot,J.M. Ndegwa,J.M. Ndegwa,Joan Mativo,Agnes C. Cheruiyot,Agnes C. Cheruiyot,Redemptah Yeda,Charles Okudo,Peninah Muiruri,Ngalah S. Bidii,Lorna J. Chebon,Paul Oyieng’ Ang’ienda,Fredrick Eyase,Jacob D. Johnson,Wallace D. Bulimo,Ben Andagalu,Hoseah M. Akala,Edwin Kamau +22 more
TL;DR: Clinical efficacy studies are now required to confirm the validity of these markers and the importance of parasite genetic background, and the mechanisms of action and resistance have not been fully elucidated.
Journal ArticleDOI
Polymorphisms in the K13 Gene in Plasmodium falciparum from Different Malaria Transmission Areas of Kenya.
Zaydah R. de Laurent,Zaydah R. de Laurent,Lorna J. Chebon,Luicer A. Ingasia,Hoseah M. Akala,Ben Andagalu,Lynette Isabella Ochola-Oyier,Lynette Isabella Ochola-Oyier,Edwin Kamau,Edwin Kamau +9 more
TL;DR: The type, prevalence, and frequency of K13 mutations that varied based on the malaria ecological zones and also between the pre- and post-ACT time periods were shown.
Journal ArticleDOI
Genetic variability and population structure of Plasmodium falciparum parasite populations from different malaria ecological regions of Kenya.
TL;DR: The authors' data suggest high genetic diversity in Kenyan parasite population with the exception of parasite from Malindi where malaria has been on the decline, and the presence of significant LD suggests that there is occurrence of inbreeding in the parasite population.
Journal ArticleDOI
The Genotypic and Phenotypic Stability of Plasmodium falciparum Field Isolates in Continuous In Vitro Culture.
Redemptah Yeda,Luicer A. Ingasia,Agnes C. Cheruiyot,Charles Okudo,Lorna J. Chebon,Lorna J. Chebon,Jelagat Cheruiyot,Hoseah M. Akala,Edwin Kamau +8 more
TL;DR: Genotypic and phenotypic profiles for the three parasite-lines fluctuated from one generation to the next with no specific pattern or periodicity, which indicates parasite genetic information obtained even in short cultures is likely to be different from the natural infection parasites.