L
Lushen Li
Researcher at University of Maryland, Baltimore
Publications - 48
Citations - 653
Lushen Li is an academic researcher from University of Maryland, Baltimore. The author has contributed to research in topics: Immune system & Medicine. The author has an hindex of 13, co-authored 36 publications receiving 394 citations. Previous affiliations of Lushen Li include Southeast University.
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Journal ArticleDOI
CD4 T cell sphingosine 1-phosphate receptor (S1PR)1 and S1PR4 and endothelial S1PR2 regulate afferent lymphatic migration
Yanbao Xiong,Wenji Piao,C. Colin Brinkman,Lushen Li,Joseph M. Kulinski,Ana Olivera,Andreane Cartier,Andreane Cartier,Timothy Hla,Timothy Hla,Keli L. Hippen,Bruce R. Blazar,Susan R. Schwab,Jonathan S. Bromberg +13 more
TL;DR: Different roles for S1PRs are demonstrated in comodulating T cell and LEC functions in migration and suggest previously unknown levels of regulation of leukocytes and endothelial cells during homeostasis and immunity.
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Gut microbiota–dependent modulation of innate immunity and lymph node remodeling affects cardiac allograft outcomes
Jonathan S. Bromberg,Lauren E. Hittle,Yanbao Xiong,Vikas Saxena,Eoghan M. Smyth,Lushen Li,Tianshu Zhang,Chelsea Wagner,W. Florian Fricke,Thomas Simon,C. Colin Brinkman,Emmanuel F. Mongodin +11 more
TL;DR: Analysis of mesenteric and peripheral lymph node structure showed that B. pseudolongum gavage resulted in a higher laminin α4/α5 ratio in the lymph node cortical ridge, indicative of a suppressive environment, while D. desulfuricans results in a lower lamination ratio, supportive of inflammation.
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Discovery and preliminary evaluation of 2-aminobenzamide and hydroxamate derivatives containing 1,2,4-oxadiazole moiety as potent histone deacetylase inhibitors.
Jin Cai,Hongtao Wei,Kwon Ho Hong,Xiaoqing Wu,Meng Cao,Xi Zong,Lushen Li,Chunlong Sun,Junqing Chen,Min Ji +9 more
TL;DR: The results suggest that 2-aminobenzamide and hydroxamate derivatives may be promising lead compounds for the development of novel anti-tumor drug potentially via inhibiting HDACs.
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A selective fluorescent turn-on probe for imaging peroxynitrite in living cells and drug-damaged liver tissues
TL;DR: The probe was successfully applied for imaging ONOO- in living cells and drug-damaged liver tissues with low cytotoxicity, demonstrating the probe KC-ONOO has great potential to further elucidate more biological roles of ONOO-.
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An acetate-based NIR fluorescent probe for selectively imaging of hydrogen peroxide in living cells and in vivo
TL;DR: A new near-infrared (NIR) fluorescence probe was designed and synthesized, which has the great competence to monitor endogenous H2O2 in cells, tissues, and in vivo but also has the huge potentiality to be employed in the diagnosis of H 2O2-related cancers.