L
Lutz Riethdorf
Researcher at University of Hamburg
Publications - 34
Citations - 2752
Lutz Riethdorf is an academic researcher from University of Hamburg. The author has contributed to research in topics: Breast cancer & Carcinogenesis. The author has an hindex of 23, co-authored 34 publications receiving 2699 citations. Previous affiliations of Lutz Riethdorf include Praxis.
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Journal ArticleDOI
Ki-67, cyclin E, and p16INK4 are complimentary surrogate biomarkers for human papilloma virus-related cervical neoplasia.
Jeffrey T. Keating,Aida Cviko,Sabine Riethdorf,Lutz Riethdorf,Bradley J. Quade,Deqin Sun,Stefan Duensing,Ellen E. Sheets,Karl Münger,Christopher P. Crum +9 more
TL;DR: Ki-67, cyclin E, and p16 are complementary surrogate biomarkers for HPV-related preinvasive squamous cervical disease and use of these biomarkers in combination for resolving diagnostic problems, with an appreciation of potential background staining, is recommended.
Journal ArticleDOI
Comparative genomic hybridization of ductal carcinoma in situ of the breast-evidence of multiple genetic pathways.
Horst Buerger,Friedrich Otterbach,Ronald Simon,Christopher Poremba,Raihanatou Diallo,Thomas Decker,Lutz Riethdorf,C. Brinkschmidt,Barbara Dockhorn-Dworniczak,Werner Boecker +9 more
TL;DR: Analysis of paraffin‐embedded specimens of DCIS and six associated invasive carcinomas revealed a genetic pattern almost identical to the one seen in the DCIS counterpart, characterize DCIS as a genetically far‐advanced, heterogeneous lesion and as a direct precursor of invasive breast cancer.
Journal Article
Molecular signature associated with bone marrow micrometastasis in human breast cancer
Ute Woelfle,Jacqueline Cloos,Guido Sauter,Lutz Riethdorf,Fritz Jänicke,Paul J. van Diest,Ruud H. Brakenhoff,Klaus Pantel +7 more
TL;DR: In this paper, the authors used bone marrow (BM) as an indicator organ for micrometastatic tumor cells in breast cancer patients without overt metastases (tumor-node metastastasis stage M(0)).
Journal Article
erbB2 Overexpression on Occult Metastatic Cells in Bone Marrow Predicts Poor Clinical Outcome of Stage I–III Breast Cancer Patients
Stephan Braun,Günter Schlimok,Isabella Heumos,G. Schaller,Lutz Riethdorf,Gert Riethmüller,Klaus Pantel +6 more
TL;DR: ErbB2 overexpression characterizes a clinically relevant subset of breast cancer micrometastases, which is a major site of metastatic relapse and cancer-related death in patients with operable primary breast cancer.
Journal ArticleDOI
Expression of Extracellular Matrix Metalloproteases Inducer on Micrometastatic and Primary Mammary Carcinoma Cells
Natalie Reimers,Kristine Zafrakas,Volker Assmann,Cornelia Egen,Lutz Riethdorf,Sabine Riethdorf,Jürgen Berger,Sebastian Ebel,Fritz Jänicke,Guido Sauter,Klaus Pantel +10 more
TL;DR: EMMPRin expression in primary tumor predicts an unfavorable prognosis in breast cancer, suggesting a crucial role of EMMPRIN in progression of human mammary carcinomas.