M
M. Graziella Persico
Researcher at International Institute of Minnesota
Publications - 25
Citations - 4499
M. Graziella Persico is an academic researcher from International Institute of Minnesota. The author has contributed to research in topics: Cripto & Vascular endothelial growth factor. The author has an hindex of 21, co-authored 25 publications receiving 4329 citations.
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Journal ArticleDOI
Synergism between vascular endothelial growth factor and placental growth factor contributes to angiogenesis and plasma extravasation in pathological conditions
Peter Carmeliet,Lieve Moons,Aernout Luttun,Valeria Vincenti,Veerle Compernolle,Maria De Mol,Yan Wu,Françoise Bono,Laetitia Devy,Heike Beck,Dimitri Scholz,Till Acker,Tina DiPalma,Mieke Dewerchin,Agnès Noël,Ingeborg Stalmans,Adriano Barra,S. Blacher,Thierry VandenDriessche,Annica Pontén,Ulf Eriksson,Karl H. Plate,Jean-Michel Foidart,Wolfgang Schaper,D. Stephen Charnock-Jones,Daniel J. Hicklin,Jean-Marc Herbert,Desire Collen,M. Graziella Persico +28 more
TL;DR: It is reported that embryonic angiogenesis in mice was not affected by deficiency of PlGF, andTransplantation of wild-type bone marrow rescued the impairedAngiogenesis and collateral growth in Pgf−/− mice, indicating that PlGF might have contributed to vessel growth in the adult by mobilizing bone-marrow–derived cells.
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A gene deleted in Kallmann's syndrome shares homology with neural cell adhesion and axonal path-finding molecules.
Brunella Franco,S Guioli,Antonella Pragliola,Antonella Pragliola,Barbara Incerti,Barbara Bardoni,Rossana Tonlorenzi,Romeo Carrozzo,Elena Maestrini,Maura Pieretti,Patricia Taillon-Miller,Carolyn J. Brown,Huntington F. Willard,Charles B. Lawrence,M. Graziella Persico,Giovanna Camerino,Andrea Ballabio +16 more
TL;DR: A gene has now been isolated from the critical region on Xp22.3 to which Kallmann's syndrome locus has been assigned: this gene escapes X inactivation, has a homologue on the Y chromosome, and shows an unusual pattern of conservation across species.
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Assignment of the Vascular Endothelial Growth Factor Gene to Human Chromosome 6p21.3
TL;DR: The location of the V EGF gene in the 6p21.3 region is a potential starting point for a linkage study and the isolation of YAC clones containing the VEGF gene will contribute to the construction of the physical map of this chromosomal region.
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The orphan receptor ALK7 and the Activin receptor ALK4 mediate signaling by Nodal proteins during vertebrate development
Eva Reissmann,Henrik Jörnvall,Andries Blokzijl,Olov Andersson,Chenbei Chang,Gabriella Minchiotti,M. Graziella Persico,Carlos F. Ibáñez,Ali H. Brivanlou +8 more
TL;DR: In this paper, the authors present biochemical and functional evidence that the orphan type I serine/threonine kinase receptor ALK7 acts as a receptor for mouse Nodal and Xenopus nodal-related 1 (Xnr1).
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Nodal-dependent Cripto signaling promotes cardiomyogenesis and redirects the neural fate of embryonic stem cells
Silvia Parisi,Daniela D'Andrea,C. T. Lago,Eileen D. Adamson,M. Graziella Persico,Gabriella Minchiotti +5 more
TL;DR: Evidence is provided for a novel role of the Nodal/Cripto/Alk4 pathway in the earliest stages of cardiomyogenesis, indicating that Cripto acts early to determine the cardiac fate.