M
M. Teresa Pisabarro
Researcher at Dresden University of Technology
Publications - 81
Citations - 3473
M. Teresa Pisabarro is an academic researcher from Dresden University of Technology. The author has contributed to research in topics: Recombinase & Docking (molecular). The author has an hindex of 31, co-authored 76 publications receiving 3012 citations. Previous affiliations of M. Teresa Pisabarro include Genentech & Free University of Berlin.
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Journal ArticleDOI
A Genome-Scale RNAi Screen for Oct4 Modulators Defines a Role of the Paf1 Complex for Embryonic Stem Cell Identity
Li Ding,Maciej Paszkowski-Rogacz,Anja Nitzsche,Mikolaj Slabicki,Anne Kristin Heninger,Ingrid de Vries,Ralf Kittler,Magno Junqueira,Andrej Shevchenko,Herbert Schulz,Norbert Hubner,Michael Xavier Doss,Agapios Sachinidis,Juergen Hescheler,Roberto Iacone,Konstantinos Anastassiadis,A. Francis Stewart,M. Teresa Pisabarro,Antonio Caldarelli,Ina Poser,Mirko Theis,Frank Buchholz +21 more
TL;DR: A genome-scale RNAi screen for a global survey of genes affecting ESC identity via alteration of Oct4 expression shows that the Paf1C binds to promoters of key pluripotency genes, where it is required to maintain a transcriptionally active chromatin structure.
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A repressor sequence in the juxtamembrane domain of Flt‐1 (VEGFR‐1) constitutively inhibits vascular endothelial growth factor‐dependent phosphatidylinositol 3′‐kinase activation and endothelial cell migration
Hendrik Gille,Joe Kowalski,Lanlan Yu,Helen Chen,M. Teresa Pisabarro,Terri Lynn Davis-Smyth,Napoleone Ferrara +6 more
TL;DR: A novel functional domain is defined that serves to repress Flt‐1 activity in endothelial cells and shows that a short divergent sequence is responsible for such repressor function.
Journal ArticleDOI
A Genome-Scale DNA Repair RNAi Screen Identifies SPG48 as a Novel Gene Associated with Hereditary Spastic Paraplegia
Mikolaj Slabicki,Mirko Theis,Dragomir B. Krastev,Sergey A. Samsonov,Emeline Mundwiller,Emeline Mundwiller,Emeline Mundwiller,Magno Junqueira,Maciej Paszkowski-Rogacz,Joan Teyra,Anne-Kristin Heninger,Ina Poser,Fabienne Prieur,Jeremy Truchetto,Jeremy Truchetto,Jeremy Truchetto,Christian Confavreux,Cecilia Marelli,Alexandra Durr,Jean Philippe Camdessanche,Alexis Brice,Andrej Shevchenko,M. Teresa Pisabarro,Giovanni Stevanin,Frank Buchholz +24 more
TL;DR: A novel gene in a genome-wide, double-strand break DNA repair RNAi screen is identified and shown to be involved in the neurological disease hereditary spastic paraplegia.
Journal ArticleDOI
Analysis of PDZ domain-ligand interactions using carboxyl-terminal phage display.
TL;DR: This work demonstrates the functional display of a peptide library fused to the carboxyl terminus of the M13 major coat protein and establishes car boxyl-terminal phage display as a powerful new method for mapping PDZ domain binding specificity.