M
Manuel Luypaert
Researcher at Ghent University
Publications - 5
Citations - 332
Manuel Luypaert is an academic researcher from Ghent University. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 2, co-authored 2 publications receiving 135 citations.
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Journal ArticleDOI
Benchmarking of RNA-sequencing analysis workflows using whole-transcriptome RT-qPCR expression data
Celine Everaert,Manuel Luypaert,Jesper L.V. Maag,Quek Xiu Cheng,Marcel E. Dinger,Jan Hellemans,Pieter Mestdagh +6 more
TL;DR: It is proposed that careful validation is warranted when evaluating RNA-seq based expression profiles for this specific gene set and a significant proportion of these method-specific inconsistent genes were reproducibly identified in independent datasets.
Journal ArticleDOI
WormBase in 2022—data, processes, and tools for analyzing Caenorhabditis elegans
Paul H. Davis,Magdalena Zarowiecki,Valerio Arnaboldi,Andres Andrade Becerra,Scott Cain,Juancarlos Chan,Wen J. Chen,Jaeyoung Choi,Eduardo da Veiga Beltrame,Stavros Diamantakis,Sibyl Gao,Dionysis Grigoriadis,Christian A. Grove,Todd W. Harris,Ranjana Kishore,Tuan Le,Raymond Lee,Manuel Luypaert,Hans-Michael Müller,Cecilia Nakamura,Paulo A. S. Nuin,Michael Paulini,Mark Quinton-Tulloch,Daniela Raciti,Faye H. Rodgers,Matthew Russell,Gary Schindelman,Archana Singh,Tim Stickland,Kimberly Van Auken,Qinghua Wang,Gary Williams,Adam Wright,Karen Yook,Matthew Berriman,Kevin L. Howe,Tim Schedl,Lincoln Stein,Paul W. Sternberg +38 more
TL;DR: A broad overview of the current state of WormBase in terms of data type, curation workflows, analysis, and tools, including exciting new advances for analysis of single-cell data, text mining and visualization, and the new community collaboration forum are provided.
Journal ArticleDOI
Harmonizing model organism data in the Alliance of Genome Resources
Julie Agapite,Laurent-Philippe Albou,Suzanne A. Aleksander,Micheal Alexander,Anna V Anagnostopoulos,Giulia Antonazzo,Joanna Gdula Argasinska,Valerio Arnaboldi,Helen Attrill,Andres Andrade Becerra,Susan M. Bello,Judith A. Blake,Olin Blodgett,Yvonne M. Bradford,Carol J. Bult,Scott Cain,Brian R. Calvi,Seth Carbon,Juancarlos Chan,Wen J. Chen,J. Michael Cherry,Jaeyoung Choi,Karen R. Christie,Madeline A. Crosby,Paul H. Davis,Eduardo da Veiga Beltrame,Jeff De Pons,Peter D'Eustachio,Stavros Diamantakis,M. Eileen Dolan,Gilberto dos Santos,Eric Douglass,Barbara Dunn,Anne E. Eagle,Dustin Ebert,Stacia R. Engel,David Fashena,Stephen F. Foley,K. S. Frazer,Sibyl Gao,A. C. Gibson,Felix Gondwe,Joshua L. Goodman,L. Sian Gramates,Christian A. Grove,Paul Hale,Todd W. Harris,G. Thomas Hayman,David J. Hill,Doug Howe,Kevin L. Howe,Yan Mengand Qiao-Mu Hu,Sagar Jha,James A. Kadin,Thomas C. Kaufman,Patrick Kalita,Kalpana Karra,Ranjana Kishore,Anne E. Kwitek,Stan Laulederkind,Raymond Lee,Ian Longden,Manuel Luypaert,Kevin A. MacPherson,Ryan Martin,Steven J Marygold,Beverley B. Matthews,Monica S. McAndrews,Gillian Millburn,Stuart R. Miyasato,Howie Motenko,Sierra A. T. Moxon,Hans Michael Muller,Christopher J. Mungall,Anushya Muruganujan,Tremayne Mushayahama,Harika S Nalabolu,Robert S. Nash,Patrick Ng,Paulo A. S. Nuin,Holly Paddock,Michael Paulini,Norbert Perrimon,Christian Pich,Mark Quinton-Tulloch,Daniela Raciti,Sridhar Ramachandran,Joel E. Richardson,Susan Russo Gelbart,Leyla Ruzicka,Kevin Schaper,Gary Schindelman,Mary Shimoyama,Matt Simison,David R. Shaw,Ajay Shrivatsav,Amy Singer,Marek S. Skrzypek,Constance M. Smith,Cynthia L. Smith,Lincoln Stein,Paul W. Sternberg,Christopher J. Tabone,Paul Thomas,K. Thorat,Jyothi Thota,Sabrina Toro,Monika Tomczuk,Vítor Trovisco,Marek Tutaj,Monika Tutaj,Jose-Maria Urbano,Kimberly Van Auken,Ceri E. Van Slyke,Qinghua Wang,Shur-Jen Wang,Shuai Wang,Monte Westerfield,Gary Williams,Laurens G. Wilming,Edith D. Wong,Adam Wright,Karen Yook,Magdalena Zarowiecki,Pinglei Zhou,Mark Zytkovicz +125 more
TL;DR: The Alliance has harmonized cross-organism data to provide useful comparative views of gene function, gene expression, and human disease relevance and expects other existing and emerging knowledge bases to join in the effort to provide the union of useful data and features that each knowledge base currently provides.
Journal ArticleDOI
decodeRNA- predicting non-coding RNA functions using guilt-by-association.
Steve Lefever,Jasper Anckaert,Pieter-Jan Volders,Manuel Luypaert,Jo Vandesompele,Pieter Mestdagh +5 more
TL;DR: DecodeRNA as mentioned in this paper provides functional contexts for both human lncRNAs and microRNAs in 29 cancer and 12 normal tissue types with state-of-the-art data mining and visualization options, easy access to results and a straightforward user interface.
Journal ArticleDOI
mRNA Capture Sequencing and RT-qPCR for the Detection of Pathognomonic, Novel, and Secondary Fusion Transcripts in FFPE Tissue: A Sarcoma Showcase
Anneleen Decock,David Creytens,Steve Lefever,Joni Van der Meulen,Jasper Anckaert,Ariane De Ganck,Jill Deleu,Bram De Wilde,Carolina Fierro,Scott Kuersten,Manuel Luypaert,Isabelle Rottiers,Gary P. Schroth,Sandra Steyaert,Katrien Vanderheyden,E. Vanden Eynde,Kimberly Verniers,Joke Verreth,J. Van Dorpe,Jo Vandesompele +19 more
TL;DR: This study shows that mRNA capture sequencing enhances the detection rate of pathognomonic fusions and enables the identification of novel and secondary fusion transcripts in sarcomas.