T
Todd W. Harris
Researcher at Cold Spring Harbor Laboratory
Publications - 17
Citations - 4039
Todd W. Harris is an academic researcher from Cold Spring Harbor Laboratory. The author has contributed to research in topics: WormBase & WormBook. The author has an hindex of 13, co-authored 15 publications receiving 3734 citations.
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Journal ArticleDOI
The Generic Genome Browser: A Building Block for a Model Organism System Database
Lincoln Stein,Christopher J. Mungall,ShengQiang Shu,Michael Caudy,Marco Mangone,Allen Day,Elizabeth Nickerson,Jason E. Stajich,Todd W. Harris,Adrian Arva,Suzanna E. Lewis +10 more
TL;DR: The Generic Genome Browser (GBrowse) is described, a Web-based application for displaying genomic annotations and other features and easy integration with other components of a model organism system Web site.
Journal ArticleDOI
The genome sequence of Caenorhabditis briggsae: A platform for comparative genomics
Lincoln Stein,Zhirong Bao,Zhirong Bao,Darin Blasiar,Thomas Blumenthal,Michael R. Brent,Nansheng Chen,Asif T. Chinwalla,Laura Clarke,Chris Clee,Avril Coghlan,Alan Coulson,Alan Coulson,Peter D'Eustachio,Peter D'Eustachio,David H. A. Fitch,Lucinda Fulton,Robert E Fulton,Sam Griffiths-Jones,Todd W. Harris,LaDeana W. Hillier,LaDeana W. Hillier,Ravi Kamath,Patricia E. Kuwabara,Elaine R. Mardis,Marco A. Marra,Marco A. Marra,Tracie L. Miner,Patrick Minx,James C. Mullikin,James C. Mullikin,Robert W. Plumb,Jane Rogers,Jacqueline E. Schein,Jacqueline E. Schein,Marc Sohrmann,John Spieth,Jason E. Stajich,Chaochun Wei,David Willey,Richard K. Wilson,Richard Durbin,Robert H. Waterston,Robert H. Waterston +43 more
TL;DR: Comparisons of the two genomes exhibit extensive colinearity, and the rate of divergence appears to be higher in the chromosomal arms than in the centers, which will help to understand the evolutionary forces that mold nematode genomes.
Journal ArticleDOI
WormBase: a multi‐species resource for nematode biology and genomics
Todd W. Harris,Nansheng Chen,Fiona Cunningham,Marcela K. Tello-Ruiz,Igor Antoshechkin,Carol Bastiani,Tamberlyn Bieri,Darin Blasiar,Keith Bradnam,Juancarlos Chan,Chao-Kung Chen,Wen J. Chen,Paul H. Davis,Eimear E. Kenny,Ranjana Kishore,Daniel Lawson,Raymond Lee,Hans-Michael Müller,Cecilia Nakamura,Philip Ozersky,Andrei Petcherski,Anthony Rogers,Aniko Sabo,Erich M. Schwarz,Kimberly Van Auken,Qinghua Wang,Richard Durbin,John Spieth,Paul W. Sternberg,Lincoln Stein +29 more
TL;DR: The nearly complete genomic sequence and comparative analyses of the closely related species Caenorhabditis briggsae have been integrated into WormBase, including gene predictions, ortholog assignments and a new synteny viewer to display the relationships between the two species.
Journal ArticleDOI
WormBase: a comprehensive data resource for Caenorhabditis biology and genomics
Nansheng Chen,Todd W. Harris,Igor Antoshechkin,Carol Bastiani,Tamberlyn Bieri,Darin Blasiar,Keith Bradnam,Payan Canaran,Juancarlos Chan,Chao-Kung Chen,Wen J. Chen,Fiona Cunningham,Paul H. Davis,Eimear E. Kenny,Ranjana Kishore,Daniel Lawson,Raymond Lee,Hans-Michael Müller,Cecilia Nakamura,Shraddha Pai,Philip Ozersky,Andrei Petcherski,Anthony Rogers,Aniko Sabo,Erich M. Schwarz,Kimberly Van Auken,Qinghua Wang,Richard Durbin,John Spieth,Paul W. Sternberg,Lincoln Stein +30 more
TL;DR: Internally, the database models are restructured to rationalize the representation of genes and to prepare the system to accept the genome sequences of three additional Caenorhabditis species over the coming year.
Journal ArticleDOI
WormBook: the online review of Caenorhabditis elegans biology
Lisa R. Girard,Tristan J. Fiedler,Todd W. Harris,Felicia Carvalho,Igor Antoshechkin,Michael Han,Paul W. Sternberg,Lincoln Stein,Martin Chalfie +8 more
TL;DR: WormBook () is an open-access, online collection of original, peer-reviewed chapters on the biology of Caenorhabditis elegans and related nematodes that represents a generic publishing infrastructure that is easily adaptable to other research communities to facilitate the dissemination of knowledge in the field.