M
Marcus Dörr
Researcher at Greifswald University Hospital
Publications - 398
Citations - 19265
Marcus Dörr is an academic researcher from Greifswald University Hospital. The author has contributed to research in topics: Population & Medicine. The author has an hindex of 56, co-authored 335 publications receiving 13711 citations. Previous affiliations of Marcus Dörr include University of Greifswald & Boston University.
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Journal ArticleDOI
Meta-analysis of epigenome-wide association studies of carotid intima-media thickness
Eliana Portilla-Fernandez,Shih-Jen Hwang,Rory P. Wilson,Jane Maddock,W. David Hill,Alexander Teumer,Pashupati P. Mishra,Jennifer A. Brody,Roby Joehanes,Symen Ligthart,Mohsen Ghanbari,Maryam Kavousi,Anton J.M. Roks,A.H. Jan Danser,Daniel Levy,Annette Peters,Sahar Ghasemi,Ulf Schminke,Marcus Dörr,Hans J. Grabe,Terho Lehtimäki,Mika Kähönen,Mikko Hurme,Traci M. Bartz,Nona Sotoodehnia,Joshua C. Bis,Joachim Thiery,Wolfgang Koenig,Wolfgang Koenig,Ken K. Ong,Jordana T. Bell,Christine Meisinger,Joanna M. Wardlaw,John M. Starr,Jochen Seissler,Cornelia Then,Wolfgang Rathmann,M. Arfan Ikram,Bruce M. Psaty,Olli T. Raitakari,Olli T. Raitakari,Henry Völzke,Ian J. Deary,Andrew Wong,Melanie Waldenberger,Christopher J. O'Donnell,Christopher J. O'Donnell,Abbas Dehghan +47 more
TL;DR: In this paper, the potential causal role of DNA methylation in the link between atherosclerotic cardiovascular risk factors and common carotid intima-media thickness (cIMT) was investigated.
Journal ArticleDOI
Mendelian randomization suggests non-causal associations of testosterone with cardiometabolic risk factors and mortality
Robin Haring,Alexander Teumer,Uwe Völker,Marcus Dörr,M. Nauck,Reiner Biffar,Henry Völzke,Sebastian E. Baumeister,Henri Wallaschofski +8 more
TL;DR: In this article, the authors used two-stage least square regression models with previously identified polymorphisms at the SHBG gene (rs12150660) and X chromosome (rs5934505) as multiple genetic instruments in an instrumental variable (IV) approach, also known as Mendelian randomization.
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One simple claudication question as first step in Peripheral Arterial Disease (PAD) screening: A meta-analysis of the association with reduced Ankle Brachial Index (ABI) in 27,945 subjects.
Arne Kieback,Christine Espinola-Klein,Claudia Lamina,Susanne Moebus,Daniel Tiller,Roberto Lorbeer,Andreas Schulz,Christa Meisinger,Daniel Medenwald,Raimund Erbel,Alexander Kluttig,Philipp S. Wild,Florian Kronenberg,Knut Kröger,Till Ittermann,Marcus Dörr +15 more
TL;DR: Asking only one question about claudication was able to identify many individuals with a high likelihood of a reduced ABI with markedly higher sensitivity and only slightly reduced specificity compared to more complex questionnaires.
Journal ArticleDOI
Combination of electrocardiographic and echocardiographic information identifies individuals prone to a progressive increase in left ventricular mass over 5 years.
Thorsten Reffelmann,Marcus Dörr,Henry Völzke,Jan A. Kors,Jörg Ruppert,Daniel M. Robinson,Stephan B. Felix +6 more
TL;DR: The relationship of electrocardiographic and echocardiographic information on left ventricular mass may identify individuals at risk for developing progressive increase in left vent cardiac mass.
Journal ArticleDOI
From heterogeneous healthcare data to disease-specific biomarker networks: A hierarchical Bayesian network approach
Ann-Kristin Becker,Marcus Dörr,Stephan B. Felix,Fabian Frost,Hans J. Grabe,Markus M. Lerch,Matthias Nauck,Uwe Völker,Henry Völzke,Lars Kaderali +9 more
TL;DR: This work introduces an entirely data-driven and automated approach to reveal disease-associated biomarker and risk factor networks from heterogeneous and high-dimensional healthcare data, and presents an optimization algorithm for the adaptive refinement of group Bayesian networks to account for a specific target variable, like a disease.