M
María Ibáñez-Vea
Researcher at University of Southern Denmark
Publications - 15
Citations - 748
María Ibáñez-Vea is an academic researcher from University of Southern Denmark. The author has contributed to research in topics: Cancer cell & Tumor microenvironment. The author has an hindex of 10, co-authored 15 publications receiving 525 citations.
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Journal ArticleDOI
PDL1 Signals through Conserved Sequence Motifs to Overcome Interferon-Mediated Cytotoxicity.
Maria Gato-Cañas,Miren Zuazo,Hugo Arasanz,María Ibáñez-Vea,Laura Lorenzo,Gonzalo Fernandez-Hinojal,R. Vera,Cristian Smerdou,Eva Martisova,Imanol Arozarena,Claudia Wellbrock,Diana Llopiz,Marta Ruiz,Pablo Sarobe,Karine Breckpot,Grazyna Kochan,David Escors +16 more
TL;DR: PDL1 cell-intrinsic signaling protects cancer cells from interferon (IFN) cytotoxicity and accelerates tumor progression and reveals a mode of action of PDL1 in cancer cells as a first line of defense against IFN cytot toxicity.
Journal ArticleDOI
PD1 signal transduction pathways in T cells
Hugo Arasanz,Maria Gato-Cañas,Miren Zuazo,María Ibáñez-Vea,Karine Breckpot,Grazyna Kochan,David Escors +6 more
TL;DR: The current knowledge on PD1-dependent intracellular signaling pathways, and the consequences of disrupting PD1 signal transduction are reviewed.
Journal ArticleDOI
Quantitative proteomics analysis of platelet-derived microparticles reveals distinct protein signatures when stimulated by different physiological agonists.
Marco Milioli,María Ibáñez-Vea,Simone Sidoli,Giuseppe Palmisano,Maria Careri,Martin R. Larsen +5 more
TL;DR: The protein profile of PMPs obtained by performing four different activation protocols using mass spectrometry-based quantitative proteomics is investigated to suggest a biological link between agonist strength and proteins associated to platelet mediated processes such as activation and degranulation.
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Simultaneous Enrichment of Cysteine-containing Peptides and Phosphopeptides Using a Cysteine-specific Phosphonate Adaptable Tag (CysPAT) in Combination with titanium dioxide (TiO2) Chromatography
Honggang Huang,Martin Haar Petersen,María Ibáñez-Vea,Pernille Lassen,Martin R. Larsen,Giuseppe Palmisano,Giuseppe Palmisano +6 more
TL;DR: The CysPAT strategy is a straight forward, easy and promising method for studying redox proteomics and the simultaneous enrichment strategy offers an excellent solution for characterization of cross-talk between phosphorylation and redox induced reversible cysteine modifications.
Journal ArticleDOI
Glycomic analysis of gastric carcinoma cells discloses glycans as modulators of RON receptor tyrosine kinase activation in cancer
Stefan Mereiter,Ana Magalhães,Barbara Adamczyk,Chunsheng Jin,Andreia Almeida,Lylia Drici,María Ibáñez-Vea,Catarina Gomes,José Alexandre Ferreira,Luís Pedro Afonso,Lúcio Lara Santos,Martin R. Larsen,Daniel Kolarich,Niclas G. Karlsson,Celso A. Reis +14 more
TL;DR: The overexpression of ST3GAL4 interferes with the overall glycophenotype of cancer cells affecting a multitude of key proteins involved in malignancy, and points to an integrative tumor glycomic/proteomic-profiling for gastric cancer patients' stratification.