M
Maria Nesterova
Researcher at National Institutes of Health
Publications - 73
Citations - 3290
Maria Nesterova is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Protein kinase A & PRKAR1A. The author has an hindex of 33, co-authored 73 publications receiving 3091 citations.
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Journal ArticleDOI
Involvement of microtubules in the regulation of Bcl2 phosphorylation and apoptosis through cyclic AMP-dependent protein kinase.
Rakesh K. Srivastava,Aparna R. Srivastava,Stanley J. Korsmeyer,Maria Nesterova,Yoon S. Cho-Chung,Dan L. Longo +5 more
TL;DR: The microtubule-damaging drugs paclitaxel, vincristine, and vinblastine induced Bcl2 hyperphosphorylation and apoptosis in MCF-7 and MDA-MB-231 cells and reduced B cl2-Bax dimerization, suggesting that there may be a signaling cascade induced by agents that disrupt or damage the cytoskeleton that is distinct from but related to the cellular response to DNA damage.
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The role of germline AIP, MEN1, PRKAR1A, CDKN1B and CDKN2C mutations in causing pituitary adenomas in a large cohort of children, adolescents, and patients with genetic syndromes.
Constantine A. Stratakis,Maria A. Tichomirowa,Sosipatros Boikos,Monalisa F. Azevedo,Maya Lodish,Marco Martari,Somya Verma,Adrian Daly,Margarita Raygada,Meg Keil,Jason Papademetriou,Limor Drori-Herishanu,Anelia Horvath,Kit Man Tsang,Maria Nesterova,Sherry Franklin,Jean-François Vanbellinghen,Vincent Bours,Roberto Salvatori,Albert Beckers +19 more
TL;DR: The role of germline AIP, MEN1, PRKAR1A, CDKN1B and CDKN2C mutations in causing pituitary adenomas in a large cohort of children, adolescents, and patients with genetic syndromes is investigated.
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cAMP-dependent protein kinase: role in normal and malignant growth
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Succinate dehydrogenase (SDH) D subunit (SDHD) inactivation in a growth-hormone-producing pituitary tumor: a new association for SDH?
Paraskevi Xekouki,Karel Pacak,Madson Q. Almeida,Christopher A. Wassif,Pierre Rustin,Maria Nesterova,Maria de la Luz Sierra,Joey C. Matro,Evan R. Ball,Monalisa F. Azevedo,Anelia Horvath,Charalampos Lyssikatos,Martha Quezado,Nicholas J. Patronas,Barbara Ferrando,Barbara Pasini,Aristides Lytras,George Tolis,Constantine A. Stratakis +18 more
TL;DR: SDHD loss of heterozygosity, down-regulation of protein in the GH-secreting adenoma, and decreased SDH enzymatic activity supports SDHD's involvement in the pituitary tumor formation in this patient.
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Clinical and Genetic Heterogeneity, Overlap with Other Tumor Syndromes, and Atypical Glucocorticoid Hormone Secretion in Adrenocorticotropin-Independent Macronodular Adrenal Hyperplasia Compared with Other Adrenocortical Tumors
Hui-Pin Hsiao,Lawrence S. Kirschner,Isabelle Bourdeau,Margaret F. Keil,Sosipatros Boikos,Somya Verma,Audrey Robinson-White,Maria Nesterova,André Lacroix,Constantine A. Stratakis +9 more
TL;DR: AIMAH is a clinically and genetically heterogeneous disorder that can be associated with various genetic defects and aberrant hormone receptors; UFCs and other measures of adrenocortical activity can be misleadingly normal.