M
Marjolène Straube
Researcher at University of Paris
Publications - 20
Citations - 865
Marjolène Straube is an academic researcher from University of Paris. The author has contributed to research in topics: Gut flora & Internal medicine. The author has an hindex of 9, co-authored 12 publications receiving 450 citations. Previous affiliations of Marjolène Straube include Paris Diderot University & French Institute of Health and Medical Research.
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Journal ArticleDOI
Impaired Aryl Hydrocarbon Receptor Ligand Production by the Gut Microbiota Is a Key Factor in Metabolic Syndrome.
Jane M. Natividad,Allison Agus,Julien Planchais,Bruno Lamas,Bruno Lamas,Anne-Charlotte Jarry,Rebeca Martín,Marie-Laure Michel,Caroline Chong-Nguyen,Ronan Roussel,Ronan Roussel,Marjolène Straube,Sarah Jegou,Claire McQuitty,Maude Le Gall,Grégory Da Costa,Emmanuelle Lecornet,Chloé Michaudel,Morgane Modoux,Morgane Modoux,Jérémy Glodt,Chantal Bridonneau,Bruno Sovran,Louise Dupraz,Louise Dupraz,André Bado,Mathias L. Richard,Philippe Langella,Boris Hansel,Boris Hansel,Jean-Marie Launay,Ramnik J. Xavier,Henri Duboc,Harry Sokol,Harry Sokol,Harry Sokol +35 more
TL;DR: The role of gut microbiota-derived metabolites as a biomarker and as a basis for novel preventative or therapeutic interventions for metabolic disorders are highlighted.
Journal ArticleDOI
Fungi participate in the dysbiosis of gut microbiota in patients with primary sclerosing cholangitis
Sara Lemoinne,Astrid Kemgang,Karima Ben Belkacem,Marjolène Straube,Sarah Jegou,Christophe Corpechot,Olivier Chazouillères,Chantal Housset,Harry Sokol +8 more
TL;DR: It is demonstrated that bacteria and fungi contribute to gut dysbiosis in PSC, for the first time, and the gut microbiota of patients with PSC exhibited a strong disruption in bacteria-fungi correlation network, suggesting an alteration in the interkingdom crosstalk.
Journal ArticleDOI
Enterobacteriaceae are essential for the modulation of colitis severity by fungi
Bruno Sovran,Julien Planchais,Sarah Jegou,Marjolène Straube,Bruno Lamas,Jane M. Natividad,Allison Agus,Louise Dupraz,Jérémy Glodt,Grégory Da Costa,Marie-Laure Michel,Philippe Langella,Mathias L. Richard,Harry Sokol,Harry Sokol +14 more
TL;DR: Fungal colonization of the gut is affected by the Enterobacteriaceae population, indirectly modifying effects of mycobiome on the host, providing new insights into the role of inter-kingdom functional interactions in intestinal physiopathology and potentially in IBD.
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Microbiota tryptophan metabolism induces aryl hydrocarbon receptor activation and improves alcohol-induced liver injury.
Laura Wrzosek,Dragos Ciocan,Cindy Hugot,Madeleine Spatz,Margot Dupeux,Camille Houron,Vanessa Liévin-Le Moal,Virginie Puchois,Gladys Ferrere,Nicolas Trainel,Françoise Mercier-Nomé,Sylvère Durand,Guido Kroemer,Cosmin Sebastian Voican,Patrick Emond,Marjolène Straube,Harry Sokol,Gabriel Perlemuter,Anne-Marie Cassard,Anne-Marie Cassard +19 more
TL;DR: Improvement of alcoholic liver disease by targeting the intestinal microbiota involves the AhR pathway, which should be considered as a new therapeutic target.
Journal ArticleDOI
Gut Microbiota-Stimulated Innate Lymphoid Cells Support β-Defensin 14 Expression in Pancreatic Endocrine Cells, Preventing Autoimmune Diabetes.
Michela Miani,Julie Le Naour,Emmanuelle Waeckel-Enée,Subash chand Verma,Marjolène Straube,Patrick Emond,Bernhard Ryffel,Bernhard Ryffel,Peter van Endert,Harry Sokol,Harry Sokol,Julien Diana +11 more
TL;DR: It is revealed that gut microbiota conditioned innate lymphoid cells (ILCs) induce the expression of mouse β-defensin 14 by pancreatic endocrine cells, preventing autoimmune diabetes in the non-obese diabetic (NOD) mice.