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André Bado
Researcher at University of Paris
Publications - 133
Citations - 6461
André Bado is an academic researcher from University of Paris. The author has contributed to research in topics: Leptin & Leptin receptor. The author has an hindex of 36, co-authored 117 publications receiving 5773 citations. Previous affiliations of André Bado include French Institute of Health and Medical Research & Paris Diderot University.
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Journal ArticleDOI
The stomach is a source of leptin
André Bado,S. Levasseur,Samir Attoub,Stéphanie Kermorgant,J.-P. Laigneau,Marie-Noëlle Bortoluzzi,L. Moizo,Thérèse Lehy,Michèle Guerre-Millo,Yannick Le Marchand-Brustel,Miguel J.M. Lewin +10 more
TL;DR: It is shown that leptin messenger RNA and leptin protein are present in rat gastric epithelium, and that cells in the glands of the gastric fundic mucosa are immunoreactive for leptin, indicating that gastric leptin may be involved in early CCK-mediated effects activated by food intake, possibly including satiety.
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Intestinal microbiota determines development of non-alcoholic fatty liver disease in mice
Tiphaine Le Roy,Marta Llopis,Patricia Lepage,Aurélia Bruneau,Sylvie Rabot,Claudia Bevilacqua,Patrice Martin,Catherine Philippe,Francine Walker,André Bado,Gabriel Perlemuter,Anne-Marie Cassard-Doulcier,Philippe Gérard +12 more
TL;DR: Differences in microbiota composition can determine response to a high-fat diet in mice, and results demonstrate that the gut microbiota contributes to the development of NAFLD independently of obesity.
Journal ArticleDOI
Leptin secretion and leptin receptor in the human stomach
Iradj Sobhani,André Bado,C. Vissuzaine,Marion Buyse,Stéphanie Kermorgant,J.-P. Laigneau,Samir Attoub,Thérèse Lehy,Dominique Hénin,M. Mignon,Miguel J.M. Lewin +10 more
TL;DR: These data provide the first evidence of the presence of leptin and leptin receptor proteins in the human stomach and suggest that gastric epithelial cells may be direct targets for leptin.
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Impaired Aryl Hydrocarbon Receptor Ligand Production by the Gut Microbiota Is a Key Factor in Metabolic Syndrome.
Jane M. Natividad,Allison Agus,Julien Planchais,Bruno Lamas,Bruno Lamas,Anne-Charlotte Jarry,Rebeca Martín,Marie-Laure Michel,Caroline Chong-Nguyen,Ronan Roussel,Ronan Roussel,Marjolène Straube,Sarah Jegou,Claire McQuitty,Maude Le Gall,Grégory Da Costa,Emmanuelle Lecornet,Chloé Michaudel,Morgane Modoux,Morgane Modoux,Jérémy Glodt,Chantal Bridonneau,Bruno Sovran,Louise Dupraz,Louise Dupraz,André Bado,Mathias L. Richard,Philippe Langella,Boris Hansel,Boris Hansel,Jean-Marie Launay,Ramnik J. Xavier,Henri Duboc,Harry Sokol,Harry Sokol,Harry Sokol +35 more
TL;DR: The role of gut microbiota-derived metabolites as a biomarker and as a basis for novel preventative or therapeutic interventions for metabolic disorders are highlighted.
Journal ArticleDOI
Liver adenosine monophosphate-activated kinase-alpha2 catalytic subunit is a key target for the control of hepatic glucose production by adiponectin and leptin but not insulin.
Fabrizio Andreelli,Marc Foretz,Claude Knauf,Patrice D. Cani,Christophe Perrin,Miguel A. Iglesias,Bruno Pillot,André Bado,François Tronche,Gilles Mithieux,Sophie Vaulont,Rémy Burcelin,Benoit Viollet +12 more
TL;DR: It is shown that the hepatic AMPKalpha2 isoform is essential for suppressing hepatic glucose production and maintaining fasting blood glucose levels in the physiological range and it is demonstrated that regulation of hepatics glucose production by leptin and adiponectin, but not insulin, requires hepatic AmPK alpha2 activity.