B
Bruno Sovran
Researcher at Institut national de la recherche agronomique
Publications - 13
Citations - 890
Bruno Sovran is an academic researcher from Institut national de la recherche agronomique. The author has contributed to research in topics: Medicine & Chemistry. The author has an hindex of 5, co-authored 5 publications receiving 499 citations. Previous affiliations of Bruno Sovran include Université Paris-Saclay.
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Journal ArticleDOI
Impaired Aryl Hydrocarbon Receptor Ligand Production by the Gut Microbiota Is a Key Factor in Metabolic Syndrome.
Jane M. Natividad,Allison Agus,Julien Planchais,Bruno Lamas,Bruno Lamas,Anne-Charlotte Jarry,Rebeca Martín,Marie-Laure Michel,Caroline Chong-Nguyen,Ronan Roussel,Ronan Roussel,Marjolène Straube,Sarah Jegou,Claire McQuitty,Maude Le Gall,Grégory Da Costa,Emmanuelle Lecornet,Chloé Michaudel,Morgane Modoux,Morgane Modoux,Jérémy Glodt,Chantal Bridonneau,Bruno Sovran,Louise Dupraz,Louise Dupraz,André Bado,Mathias L. Richard,Philippe Langella,Boris Hansel,Boris Hansel,Jean-Marie Launay,Ramnik J. Xavier,Henri Duboc,Harry Sokol,Harry Sokol,Harry Sokol +35 more
TL;DR: The role of gut microbiota-derived metabolites as a biomarker and as a basis for novel preventative or therapeutic interventions for metabolic disorders are highlighted.
Journal ArticleDOI
Bilophila wadsworthia aggravates high fat diet induced metabolic dysfunctions in mice
Jane M. Natividad,Bruno Lamas,Bruno Lamas,Hang-Phuong Pham,Marie Laure Michel,Dominique Rainteau,Chantal Bridonneau,Grégory Da Costa,Johan E. T. van Hylckama Vlieg,Bruno Sovran,Celia Chamignon,Julien Planchais,Mathias L. Richard,Philippe Langella,Patrick Veiga,Harry Sokol +15 more
TL;DR: It is shown that B. wadsworthia aggravates high fat diet induced metabolic dysfunctions and its suppression, both pharmacologically or mediated by Lactobacillus rhamnosus, limits the severity of metabolic impairment.
Journal ArticleDOI
Genetic deficiency of indoleamine 2,3-dioxygenase promotes gut microbiota-mediated metabolic health.
Ludivine Laurans,Nicolas Venteclef,Yacine Haddad,Mouna Chajadine,Fawaz Alzaid,Sarvenaz Metghalchi,Bruno Sovran,Raphael G. P. Denis,Julien Dairou,Marina Cardellini,J M Moreno-Navarrete,Marjolene Straub,Sarah Jegou,Claire McQuitty,Thomas Viel,Bruno Esposito,Bertrand Tavitian,Jacques Callebert,Serge Luquet,Massimo Federici,José Manuel Fernández-Real,Rémy Burcelin,Jean-Marie Launay,Alain Tedgui,Ziad Mallat,Ziad Mallat,Harry Sokol,Harry Sokol,Harry Sokol,Soraya Taleb +29 more
TL;DR: It is shown that obesity is associated with an increase of intestinal indoleamine 2,3-dioxygenase activity, which shifts tryptophan metabolism from indole derivative and interleukin-22 production toward kynurenine production, which suggests indoleamines 2, 3-diaxgenase as a potential therapeutic target.
Journal ArticleDOI
Enterobacteriaceae are essential for the modulation of colitis severity by fungi
Bruno Sovran,Julien Planchais,Sarah Jegou,Marjolène Straube,Bruno Lamas,Jane M. Natividad,Allison Agus,Louise Dupraz,Jérémy Glodt,Grégory Da Costa,Marie-Laure Michel,Philippe Langella,Mathias L. Richard,Harry Sokol,Harry Sokol +14 more
TL;DR: Fungal colonization of the gut is affected by the Enterobacteriaceae population, indirectly modifying effects of mycobiome on the host, providing new insights into the role of inter-kingdom functional interactions in intestinal physiopathology and potentially in IBD.
Journal ArticleDOI
Card9 mediates susceptibility to intestinal pathogens through microbiota modulation and control of bacterial virulence.
Bruno Lamas,Marie-Laure Michel,Nadine Waldschmitt,Hang-Phuong Pham,Vassiliki Zacharioudaki,Louise Dupraz,Myriam Delacre,Jane M. Natividad,Grégory Da Costa,Julien Planchais,Bruno Sovran,Chantal Bridonneau,Adrien Six,Philippe Langella,Mathias L. Richard,Mathias Chamaillard,Harry Sokol +16 more
TL;DR: CARD9 modulates the susceptibility to intestinal infection by controlling the pathogen virulence in a microbiota-dependent and microbiota-independent manner.