M
Marta Córcoles Parada
Researcher at University of Castilla–La Mancha
Publications - 5
Citations - 46
Marta Córcoles Parada is an academic researcher from University of Castilla–La Mancha. The author has contributed to research in topics: Neurofibrillary tangle & Temporal lobe. The author has an hindex of 1, co-authored 5 publications receiving 8 citations.
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Journal ArticleDOI
Three-dimensional mapping of neurofibrillary tangle burden in the human medial temporal lobe
Paul A. Yushkevich,M. López,Maria Mercedes Iniguez de Onzono Martin,Ranjit Ittyerah,Sydney Lim,Sadhana Ravikumar,Madigan L. Bedard,Stephen Pickup,Weixia Liu,Jiancong Wang,Ling Yu Hung,Jade Lasserve,Nicolas Vergnet,Long Xie,Mengjin Dong,Salena Cui,Lauren McCollum,John L. Robinson,Theresa Schuck,Robin de Flores,Murray Grossman,M. Dylan Tisdall,Karthik Prabhakaran,Gabor Mizsei,Sandhitsu R. Das,Emilio Artacho-Pérula,María del Mar Arroyo Jiménez,Marı’a Pilar Marcos Raba,Francisco Javier Molina Romero,Sandra Cebada Sánchez,José Carlos Delgado González,Carlos de la Rosa-Prieto,Marta Córcoles Parada,Edward B. Lee,John Q. Trojanowski,Daniel T. Ohm,Laura Wisse,David A. Wolk,David J. Irwin,Ricardo Insausti +39 more
TL;DR: In this paper, the authors constructed 3D quantitative maps of neurofibrillary tangle burden in the medial temporal lobe at individual and group levels and found significant variation along the anterior-posterior axis.
Journal ArticleDOI
Ex vivo MRI atlas of the human medial temporal lobe: characterizing neurodegeneration due to tau pathology.
Sadhana Ravikumar,Laura E.M. Wisse,Laura E.M. Wisse,Sydney Lim,Ranjit Ittyerah,Long Xie,Madigan L. Bedard,Sandhitsu R. Das,Edward B. Lee,M. Dylan Tisdall,Karthik Prabhakaran,Jacqueline M. Lane,John A. Detre,Gabor Mizsei,John Q. Trojanowski,John L. Robinson,Theresa Schuck,Murray Grossman,Emilio Artacho-Pérula,Maria Mercedes Iniguez de Onzono Martin,María del Mar Arroyo Jiménez,Monica Munoz,Francisco Javier Molina Romero,Maria del Pilar Marcos Rabal,Sandra Cebada Sánchez,José Carlos Delgado González,Carlos de la Rosa Prieto,Marta Córcoles Parada,David J. Irwin,David A. Wolk,Ricardo Insausti,Paul A. Yushkevich +31 more
TL;DR: In this article, the authors compared high-resolution ex vivo MRI scans of human postmortem medial temporal lobe (MTL) specimens with histology-based pathological assessments of the MTL and found significant correlations between tau pathology and thickness in the entorhinal cortex and stratum radiatum lacunosum moleculare (SRLM).
Posted ContentDOI
3D Mapping of Neurofibrillary Tangle Burden in the Human Medial Temporal Lobe
Paul A. Yushkevich,M. López,Maria Mercedes Iniguez de Onzono Martin,Ranjit Ittyerah,Sydney Lim,Sadhana Ravikumar,Madigan L. Bedard,Stephen Pickup,Weixia Liu,Jiancong Wang,Ling Yu Hung,Jade Lasserve,Nicolas Vergnet,Long Xie,Mengjin Dong,Salena Cui,Lauren McCollum,John L. Robinson,Theresa Schuck,Robin de Flores,Murray Grossman,M. Dylan Tisdall,Karthik Prabhakaran,Gabor Mizsei,Sandhitsu R. Das,Emilio Artacho-Pérula,María del Mar Arroyo Jiménez,Maria del Pilar Marcos Rabal,Francisco Javier Molina Romero,Sandra Cebada Sánchez,José Carlos Delgado González,Carlos de la Rosa-Prieto,Marta Córcoles Parada,Edward B. Lee,John Q. Trojanowski,Daniel T. Ohm,Laura Wisse,David A. Wolk,David J. Irwin,Ricardo Insausti +39 more
TL;DR: In this paper, the authors used ex vivo MRI and dense serial histological imaging in 18 human medial temporal lobe (MTL) specimens to construct 3D quantitative maps of NFT burden in the MTL at individual and group levels.
Journal ArticleDOI
High‐resolution postmortem MRI reveals TDP‐43 association with medial temporal lobe subregional atrophy: Biomarkers: Leveraging postmortem collections to validate neuroimaging
Laura E.M. Wisse,Laura E.M. Wisse,Sadhana Ravikumar,Ranjit Ittyerah,Sydney Lim,Jacqueline M. Lane,Madigan Lavery,Long Xie,John L. Robinson,Theresa Schuck,Murray Grossman,Eddie B. Lee,Dylan M. Tisdall,Karthik Prabhakaran,John A. Detre,Sandhitsu R. Das,Gabor Mizsei,Emilio Artacho-Pérula,Maria Mercedes Iniguez de Onzono Martin,María del Mar Arroyo Jiménez,Monica Munoz,Francisco Javier Molina Romero,Maria del Pilar Marcos Rabal,Sandra Cebada Sánchez,José Carlos Delgado González,Carlos de la Rosa Prieto,Marta Córcoles Parada,David J. Irwin,John Q. Trojanowski,David A. Wolk,Ricardo Insausti,Paul A. Yushkevich +31 more
TL;DR: This work investigates the association of different neurodegenerative pathologies, particularly TDP‐43, and the thickness of different MTL subregions measured on high‐resolution postmortem MRI, and examines differences along the long axis of the MTL.
Book ChapterDOI
Unfolding the Medial Temporal Lobe Cortex to Characterize Neurodegeneration Due to Alzheimer’s Disease Pathology Using Ex vivo Imaging
Sadhana Ravikumar,Laura Wisse,Sydney Lim,David J. Irwin,Ranjit Ittyerah,Long Xie,Sandhitsu R. Das,Edward B. Lee,M. Dylan Tisdall,Karthik Prabhakaran,John A. Detre,Gabor Mizsei,John Q. Trojanowski,John L. Robinson,Theresa Schuck,Murray Grossman,Emilio Artacho-Pérula,Maria Mercedes Iniguez de Onzono Martin,María del Mar Arroyo Jiménez,Monica Munoz,Francisco Javier Molina Romero,Maria del Pilar Marcos Rabal,Sandra Cebada Sánchez,José Carlos Delgado González,Carlos de la Rosa Prieto,Marta Córcoles Parada,David A. Wolk,Ricardo Insausti,Paul A. Yushkevich +28 more
TL;DR: In this paper, a topological unfolding framework was proposed to explicitly account for the sheet-like geometry of the medial temporal lobe (MTL) cortex and provide a two-dimensional reference coordinate space which can be used to implicitly register cortical folding patterns across specimens based on distance along the cortex despite large anatomical variability.