J
Jacqueline M. Lane
Researcher at Harvard University
Publications - 91
Citations - 5771
Jacqueline M. Lane is an academic researcher from Harvard University. The author has contributed to research in topics: Medicine & Chronotype. The author has an hindex of 24, co-authored 67 publications receiving 3815 citations. Previous affiliations of Jacqueline M. Lane include University Hospitals Bristol NHS Foundation Trust & Brigham and Women's Hospital.
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Journal ArticleDOI
Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression
Naomi R. Wray,Stephan Ripke,Stephan Ripke,Stephan Ripke,Manuel Mattheisen,Maciej Trzaskowski,Enda M. Byrne,Abdel Abdellaoui,Mark Adams,Esben Agerbo,Esben Agerbo,Tracy Air,Till M.F. Andlauer,Silviu Alin Bacanu,Marie Bækvad-Hansen,Marie Bækvad-Hansen,Aartjan F.T. Beekman,Tim B. Bigdeli,Elisabeth B. Binder,Elisabeth B. Binder,Douglas Blackwood,Julien Bryois,Henriette N. Buttenschøn,Henriette N. Buttenschøn,Jonas Bybjerg-Grauholm,Jonas Bybjerg-Grauholm,Na Cai,Na Cai,Enrique Castelao,Jane H. Christensen,Jane H. Christensen,Toni-Kim Clarke,Jonathan I.R. Coleman,Lucía Colodro-Conde,Baptiste Couvy-Duchesne,Nicholas John Craddock,Gregory E. Crawford,Cheynna A. Crowley,Hassan S. Dashti,Hassan S. Dashti,Gail Davies,Ian J. Deary,Franziska Degenhardt,Eske M. Derks,Nese Direk,Nese Direk,Conor V. Dolan,Erin C. Dunn,Erin C. Dunn,Thalia C. Eley,Nicholas Eriksson,Valentina Escott-Price,Farnush Hassan Farhadi Kiadeh,Hilary K. Finucane,Hilary K. Finucane,Andreas J. Forstner,Josef Frank,Helena Gaspar,Michael Gill,Paola Giusti-Rodríguez,Fernando S. Goes,Scott D. Gordon,Jakob Grove,Lynsey S. Hall,Lynsey S. Hall,Eilis Hannon,Christine Søholm Hansen,Christine Søholm Hansen,Thomas Hansen,Thomas Hansen,Stefan Herms,Stefan Herms,Ian B. Hickie,Per Hoffmann,Per Hoffmann,Georg Homuth,Carsten Horn,Jouke-Jan Hottenga,David M. Hougaard,David M. Hougaard,Ming Hu,Craig L. Hyde,Marcus Ising,Rick Jansen,Fulai Jin,Eric Jorgenson,James A. Knowles,Isaac S. Kohane,Isaac S. Kohane,Isaac S. Kohane,Julia Kraft,Warren W. Kretzschmar,Jesper Krogh,Zoltán Kutalik,Zoltán Kutalik,Jacqueline M. Lane,Jacqueline M. Lane,Yihan Li,Yun Li,Penelope A. Lind,Xiaoxiao Liu,Leina Lu,Donald J. MacIntyre,Dean F. MacKinnon,Robert Maier,Wolfgang Maier,Jonathan Marchini,Hamdi Mbarek,Patrick J. McGrath,Peter McGuffin,Sarah E. Medland,Divya Mehta,Divya Mehta,Christel M. Middeldorp,Christel M. Middeldorp,Evelin Mihailov,Yuri Milaneschi,Lili Milani,Jonathan Mill,Francis M. Mondimore,Grant W. Montgomery,Sara Mostafavi,Niamh Mullins,Matthias Nauck,Bernard Ng,Michel G. Nivard,Dale R. Nyholt,Paul F. O'Reilly,Hogni Oskarsson,Michael John Owen,Jodie N. Painter,Carsten Bøcker Pedersen,Carsten Bøcker Pedersen,Marianne Giørtz Pedersen,Marianne Giørtz Pedersen,Roseann E. Peterson,Erik Pettersson,Wouter J. Peyrot,Giorgio Pistis,Danielle Posthuma,Shaun Purcell,Jorge A. Quiroz,Per Qvist,Per Qvist,John P. Rice,Brien P. Riley,Margarita Rivera,Margarita Rivera,Saira Saeed Mirza,Richa Saxena,Richa Saxena,Robert A. Schoevers,Eva C. Schulte,Ling Shen,Jianxin Shi,Stanley I. Shyn,Engilbert Sigurdsson,Grant Sinnamon,Johannes H. Smit,Daniel J. Smith,Hreinn Stefansson,Stacy Steinberg,Craig A. Stockmeier,Fabian Streit,Jana Strohmaier,Katherine E. Tansey,Henning Teismann,Alexander Teumer,Wesley K. Thompson,Pippa A. Thomson,Thorgeir E. Thorgeirsson,Chao Tian,Matthew Traylor,Jens Treutlein,Vassily Trubetskoy,André G. Uitterlinden,Daniel Umbricht,Sandra Van der Auwera,Albert M. van Hemert,Alexander Viktorin,Peter M. Visscher,Yunpeng Wang,Yunpeng Wang,Yunpeng Wang,Bradley T. Webb,Shantel Weinsheimer,Shantel Weinsheimer,Jürgen Wellmann,Gonneke Willemsen,Stephanie H. Witt,Yang Wu,Hualin S. Xi,Jian Yang,Futao Zhang,Volker Arolt,Bernhard T. Baune,Klaus Berger,Dorret I. Boomsma,Sven Cichon,Udo Dannlowski,E. C.J. De Geus,J. Raymond DePaulo,Enrico Domenici,Katharina Domschke,Tõnu Esko,Tõnu Esko,Hans J. Grabe,Steven P. Hamilton,Caroline Hayward,Andrew C. Heath,David A. Hinds,Kenneth S. Kendler,Stefan Kloiber,Stefan Kloiber,Stefan Kloiber,Glyn Lewis,Qingqin S. Li,Susanne Lucae,Pamela F.A. Madden,Patrik K. E. Magnusson,Nicholas G. Martin,Andrew M. McIntosh,Andres Metspalu,Ole Mors,Ole Mors,Preben Bo Mortensen,Bertram Müller-Myhsok,Bertram Müller-Myhsok,Merete Nordentoft,Merete Nordentoft,Markus M. Nöthen,Michael Conlon O'Donovan,Sara A. Paciga,Nancy L. Pedersen,Brenda W.J.H. Penninx,Roy H. Perlis,David J. Porteous,James B. Potash,Martin Preisig,Marcella Rietschel,Catherine Schaefer,Thomas G. Schulze,Jordan W. Smoller,Jordan W. Smoller,Kari Stefansson,Kari Stefansson,Henning Tiemeier,Rudolf Uher,Henry Völzke,Myrna M. Weissman,Myrna M. Weissman,Thomas Werge,Thomas Werge,Thomas Werge,Ashley R. Winslow,Ashley R. Winslow,Cathryn M. Lewis,Douglas F. Levinson,Gerome Breen,Anders D. Børglum,Anders D. Børglum,Patrick F. Sullivan,Patrick F. Sullivan +262 more
TL;DR: A genome-wide association meta-analysis of individuals with clinically assessed or self-reported depression identifies 44 independent and significant loci and finds important relationships of genetic risk for major depression with educational attainment, body mass, and schizophrenia.
Journal ArticleDOI
Genetic determinants of daytime napping and effects on cardiometabolic health.
Hassan S. Dashti,Iyas Daghlas,Iyas Daghlas,Jacqueline M. Lane,Jacqueline M. Lane,Yunru Huang,Miriam S. Udler,Heming Wang,Hanna Ollila,Samuel E. Jones,Jaegil Kim,Andrew R. Wood,Michael N. Weedon,Stella Aslibekyan,Marta Garaulet,Richa Saxena,Richa Saxena +16 more
TL;DR: In this article, a genome-wide association study of self-reported daytime napping in the UK Biobank and Mendelian randomization was performed to explore causal associations with cardiometabolic outcomes.
Journal ArticleDOI
Genome-wide association analyses of chronotype in 697,828 individuals provides insights into circadian rhythms.
Samuel E. Jones,Jacqueline M. Lane,Jacqueline M. Lane,Andrew R. Wood,Vincent T. van Hees,Jessica Tyrrell,Robin N Beaumont,Aaron R. Jeffries,Hassan S. Dashti,Hassan S. Dashti,Melvyn Hillsdon,Katherine S. Ruth,Marcus A. Tuke,Hanieh Yaghootkar,Seth A. Sharp,Yingjie Jie,William D. Thompson,Jamie W. Harrison,Amy Dawes,Enda M. Byrne,Henning Tiemeier,Karla V. Allebrandt,Jack Bowden,David W. Ray,Rachel M. Freathy,Anna Murray,Diego R. Mazzotti,Philip R. Gehrman,Debbie A Lawlor,Timothy M. Frayling,Martin K. Rutter,David A. Hinds,Richa Saxena,Richa Saxena,Michael N. Weedon +34 more
TL;DR: It is shown that being a morning person is causally associated with better mental health but does not affect BMI or risk of Type 2 diabetes, and the chronotype loci associate with sleep timing.
Journal ArticleDOI
Genome-wide association study identifies genetic loci for self-reported habitual sleep duration supported by accelerometer-derived estimates
Hassan S. Dashti,Hassan S. Dashti,Steven Jones,Andrew R. Wood,Jacqueline M. Lane,Jacqueline M. Lane,Vincent T. van Hees,Heming Wang,Heming Wang,Heming Wang,Jennifer Rhodes,Jennifer Rhodes,Yanwei Song,Yanwei Song,Krunal Patel,Krunal Patel,Simon G. Anderson,Robin N Beaumont,David A. Bechtold,Jack Bowden,Brian E. Cade,Brian E. Cade,Brian E. Cade,Marta Garaulet,Simon D. Kyle,Max A. Little,Max A. Little,Andrew S. I. Loudon,Annemarie I. Luik,Frank A.J.L. Scheer,Frank A.J.L. Scheer,Frank A.J.L. Scheer,Kai Spiegelhalder,Jessica Tyrrell,Daniel J. Gottlieb,Daniel J. Gottlieb,Daniel J. Gottlieb,Henning Tiemeier,Henning Tiemeier,David W. Ray,Shaun Purcell,Timothy M. Frayling,Susan Redline,Debbie A Lawlor,Martin K. Rutter,Michael N. Weedon,Richa Saxena,Richa Saxena +47 more
TL;DR: Performing GWAS for self-reported habitual sleep duration in adults, supported by accelerometer-derived measures, and identifying genetic correlation with psychiatric and metabolic traits provides insights into the genetic basis for inter-individual variation in sleep duration implicating multiple biological pathways.
Journal ArticleDOI
Genome-wide association analyses of sleep disturbance traits identify new loci and highlight shared genetics with neuropsychiatric and metabolic traits
Jacqueline M. Lane,Jingjing Liang,Irma Vlasac,Irma Vlasac,Simon G. Anderson,Simon G. Anderson,David A. Bechtold,Jack Bowden,Richard Emsley,Shubhroz Gill,Max A. Little,Annemarie I. Luik,Andrew S. I. Loudon,Frank A.J.L. Scheer,Shaun Purcell,Shaun Purcell,Shaun Purcell,Simon D. Kyle,Debbie A Lawlor,Xiaofeng Zhu,Susan Redline,David W. Ray,Martin K. Rutter,Martin K. Rutter,Richa Saxena +24 more
TL;DR: In this paper, single and multiple-trait genome-wide association analyses of self-reported sleep duration, insomnia symptoms and excessive daytime sleepiness in the UK Biobank (n = 112,586) were performed.